Comparative electron-microscopic investigation of postmortem human heart muscle biopsy

E. Somogyi, I. Balogh, P. Sótónyi, N. A. Kerenyi

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Based on Harvard criteria findings, comparative morphological investigations on postmortem heart muscle biopsy following coronary insufficiency after sudden cardiac death have been reported. The subendothelial layer of the left ventricular wall has revealed a severe interstitial edema, various types of actin-myosin filamental destruction, mitochondrial damage, and disseminated muscle fiber necrosis. One of the first alterations observed was the change in transmembrane calcium and intracellular calcium metabolism. A decrease in succinic dehydrogenase and cytochrome oxidase activity was discovered early.

Original languageEnglish
Pages (from-to)7-13
Number of pages7
JournalAmerican Journal of Forensic Medicine and Pathology
Volume4
Issue number1
Publication statusPublished - 1983

Fingerprint

interstitial
Succinate Dehydrogenase
Myocardium
damages
Electrons
Calcium
death
Biopsy
Sudden Cardiac Death
Electron Transport Complex IV
Myosins
Actins
Edema
Necrosis
Muscles

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Pathology and Forensic Medicine
  • Law

Cite this

Comparative electron-microscopic investigation of postmortem human heart muscle biopsy. / Somogyi, E.; Balogh, I.; Sótónyi, P.; Kerenyi, N. A.

In: American Journal of Forensic Medicine and Pathology, Vol. 4, No. 1, 1983, p. 7-13.

Research output: Contribution to journalArticle

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