Comparative electron histochemistry of thiamine monophosphatase and substance P in the upper dorsal horn

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The genuine marker enzyme of primary nociceptive neurons, thiamine monophosphatase (TMPase) has been localized in the substantia gelatinosa of the rat spinal cord by means of light-and electron microscopic histochemistry; localization of substance P has been studied by light-and electron microscopic immunohistochemical methods. It has been shown that TMPase and substance P are located in two, regionally and structurally different populations of axon terminals. Substance P is contained both in Ad and in drC axons. In the postero-lateral funiculus of the white matter, substance P-positive axons establish axo-somatic synaptic contacts with large multipolar neurons of Cajal's interstitial nucleus.

Original languageEnglish
Pages (from-to)125-134
Number of pages10
JournalActa histochemica
Issue number1
Publication statusPublished - Jan 1 1986


ASJC Scopus subject areas

  • Histology
  • Cell Biology

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