FDG-PET-vizsgálatok kvantitatív kiértékelési módszereinek összehasonlító analízise.

Translated title of the contribution: Comparative analysis of quantitative evaluation methods for FDG-PET scans

László Balkay, Zoárd Krasznai, Pál Mikecz

Research output: Contribution to journalArticle

Abstract

The comparative analysis of two kinetic methods most frequently applied for the quantization of the results of FDG-PET brain scans was performed applying PET investigations and computer simulations. The analysis of the measured data and computer simulation demonstrated that the applicability of the results of SUV-methods to estimate glucose metabolic rates (GMR) as calculated by the Phelps-method (the most advanced method ) depended on the selected cerebral region. The distorted estimation was explained by the fact that the simpler models neglect dephosphorylation of the FDG-6P, and they also disregard the contribution of the intravascular activity to the tissue radioactivity. The simulations revealed the lack of a general and close positive correlation between SUV and GMR data; under special circumstances they might even change in an inverse manner.

Translated title of the contributionComparative analysis of quantitative evaluation methods for FDG-PET scans
Original languageHungarian
Pages (from-to)1251-1254
Number of pages4
JournalOrvosi hetilap
Volume143
Issue number21 Suppl 3
Publication statusPublished - May 26 2002

ASJC Scopus subject areas

  • Medicine(all)

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