Combining benzo[d]isoselenazol-3-ones with sterically hindered alicyclic amines and nitroxides

Enhanced activity as glutathione peroxidase mimics

T. Kalai, Govindasamy Mugesh, Gouriprasanna Roy, Helmut Sies, Z. Berente, K. Hideg

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Benzo[d]isoselenazol-3-ones N-substituted with sterically hindered diamagnetic and paramagnetic five- or six-membered nitroxides or their precursors, including ring-opened diselenides, exhibit synergism in glutathione peroxidase (GPx) activity.

Original languageEnglish
Pages (from-to)3564-3569
Number of pages6
JournalOrganic and Biomolecular Chemistry
Volume3
Issue number19
DOIs
Publication statusPublished - Oct 7 2005

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glutathione
Glutathione Peroxidase
Amines
amines
rings

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Chemistry(all)

Cite this

Combining benzo[d]isoselenazol-3-ones with sterically hindered alicyclic amines and nitroxides : Enhanced activity as glutathione peroxidase mimics. / Kalai, T.; Mugesh, Govindasamy; Roy, Gouriprasanna; Sies, Helmut; Berente, Z.; Hideg, K.

In: Organic and Biomolecular Chemistry, Vol. 3, No. 19, 07.10.2005, p. 3564-3569.

Research output: Contribution to journalArticle

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