Combined use of stents and coils to treat experimental wide-necked carotid aneurysms: Preliminary results

I. Szikora, L. R. Guterman, K. M. Wells, L. N. Hopkins

Research output: Contribution to journalArticle

123 Citations (Scopus)

Abstract

PURPOSE: To develop a new technique to treat wide-necked side-wall aneurysms, combining the implantation of intraarterial stents with the endosaccular placement of coils. METHODS: Bilateral side-wall aneurysms were surgically created on the carotid arteries of four dogs. In each animal, Guglielmi detachable coils were introduced into one of the aneurysms after implantation of a balloon-expandable Strecker stent within the parent artery, adjacent to the aneurysm orifice. The contralateral aneurysms were treated with coils alone. RESULTS: In two dogs, one of the stented and both nonstented aneurysms remained partially open for 4 weeks after subtotal packing with coils. In another two dogs, tight aneurysm packing with coils resulted in complete occlusion of all four aneurysms. Bulging of the coil mass resulted in 30% to 75% narrowing of the nonstented parent arteries. At 4 and 5 weeks, significant stenosis resulting from reactive hyperplasia was observed in all stented carotid arteries. CONCLUSION: Based on these preliminary results, we conclude that Guglielmi detachable coils can be introduced into an aneurysm cavity through Strecker stents. The stents allow tighter packing of wide-necked aneurysms by preventing coils from migrating or bulging into the parent arteries.

Original languageEnglish
Pages (from-to)1091-1102
Number of pages12
JournalAmerican Journal of Neuroradiology
Volume15
Issue number6
Publication statusPublished - 1994

Fingerprint

Stents
Aneurysm
Arteries
Dogs
Carotid Arteries
Hyperplasia
Pathologic Constriction

ASJC Scopus subject areas

  • Clinical Neurology
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Combined use of stents and coils to treat experimental wide-necked carotid aneurysms : Preliminary results. / Szikora, I.; Guterman, L. R.; Wells, K. M.; Hopkins, L. N.

In: American Journal of Neuroradiology, Vol. 15, No. 6, 1994, p. 1091-1102.

Research output: Contribution to journalArticle

@article{42d538e92e66420694d45b6f7aa6ca93,
title = "Combined use of stents and coils to treat experimental wide-necked carotid aneurysms: Preliminary results",
abstract = "PURPOSE: To develop a new technique to treat wide-necked side-wall aneurysms, combining the implantation of intraarterial stents with the endosaccular placement of coils. METHODS: Bilateral side-wall aneurysms were surgically created on the carotid arteries of four dogs. In each animal, Guglielmi detachable coils were introduced into one of the aneurysms after implantation of a balloon-expandable Strecker stent within the parent artery, adjacent to the aneurysm orifice. The contralateral aneurysms were treated with coils alone. RESULTS: In two dogs, one of the stented and both nonstented aneurysms remained partially open for 4 weeks after subtotal packing with coils. In another two dogs, tight aneurysm packing with coils resulted in complete occlusion of all four aneurysms. Bulging of the coil mass resulted in 30{\%} to 75{\%} narrowing of the nonstented parent arteries. At 4 and 5 weeks, significant stenosis resulting from reactive hyperplasia was observed in all stented carotid arteries. CONCLUSION: Based on these preliminary results, we conclude that Guglielmi detachable coils can be introduced into an aneurysm cavity through Strecker stents. The stents allow tighter packing of wide-necked aneurysms by preventing coils from migrating or bulging into the parent arteries.",
author = "I. Szikora and Guterman, {L. R.} and Wells, {K. M.} and Hopkins, {L. N.}",
year = "1994",
language = "English",
volume = "15",
pages = "1091--1102",
journal = "American Journal of Neuroradiology",
issn = "0195-6108",
publisher = "American Society of Neuroradiology",
number = "6",

}

TY - JOUR

T1 - Combined use of stents and coils to treat experimental wide-necked carotid aneurysms

T2 - Preliminary results

AU - Szikora, I.

AU - Guterman, L. R.

AU - Wells, K. M.

AU - Hopkins, L. N.

PY - 1994

Y1 - 1994

N2 - PURPOSE: To develop a new technique to treat wide-necked side-wall aneurysms, combining the implantation of intraarterial stents with the endosaccular placement of coils. METHODS: Bilateral side-wall aneurysms were surgically created on the carotid arteries of four dogs. In each animal, Guglielmi detachable coils were introduced into one of the aneurysms after implantation of a balloon-expandable Strecker stent within the parent artery, adjacent to the aneurysm orifice. The contralateral aneurysms were treated with coils alone. RESULTS: In two dogs, one of the stented and both nonstented aneurysms remained partially open for 4 weeks after subtotal packing with coils. In another two dogs, tight aneurysm packing with coils resulted in complete occlusion of all four aneurysms. Bulging of the coil mass resulted in 30% to 75% narrowing of the nonstented parent arteries. At 4 and 5 weeks, significant stenosis resulting from reactive hyperplasia was observed in all stented carotid arteries. CONCLUSION: Based on these preliminary results, we conclude that Guglielmi detachable coils can be introduced into an aneurysm cavity through Strecker stents. The stents allow tighter packing of wide-necked aneurysms by preventing coils from migrating or bulging into the parent arteries.

AB - PURPOSE: To develop a new technique to treat wide-necked side-wall aneurysms, combining the implantation of intraarterial stents with the endosaccular placement of coils. METHODS: Bilateral side-wall aneurysms were surgically created on the carotid arteries of four dogs. In each animal, Guglielmi detachable coils were introduced into one of the aneurysms after implantation of a balloon-expandable Strecker stent within the parent artery, adjacent to the aneurysm orifice. The contralateral aneurysms were treated with coils alone. RESULTS: In two dogs, one of the stented and both nonstented aneurysms remained partially open for 4 weeks after subtotal packing with coils. In another two dogs, tight aneurysm packing with coils resulted in complete occlusion of all four aneurysms. Bulging of the coil mass resulted in 30% to 75% narrowing of the nonstented parent arteries. At 4 and 5 weeks, significant stenosis resulting from reactive hyperplasia was observed in all stented carotid arteries. CONCLUSION: Based on these preliminary results, we conclude that Guglielmi detachable coils can be introduced into an aneurysm cavity through Strecker stents. The stents allow tighter packing of wide-necked aneurysms by preventing coils from migrating or bulging into the parent arteries.

UR - http://www.scopus.com/inward/record.url?scp=0028302797&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028302797&partnerID=8YFLogxK

M3 - Article

C2 - 8073978

AN - SCOPUS:0028302797

VL - 15

SP - 1091

EP - 1102

JO - American Journal of Neuroradiology

JF - American Journal of Neuroradiology

SN - 0195-6108

IS - 6

ER -