Combined Echo-Apexcardiographic Assessment of Left Ventricular Function in Cardiomyopathy

Nikolai Kolev, Maria Lengyel, Livia Cserhalmi, Tibor Romoda

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Eleven patients with hypertrophic obstructive cardiomyopathy (HOCM) and 9 patients with congestive cardiomyopathy (COGM) were studied to determine the usefulness of mean normalized velocity of circumferential fiber shortening (VCFs), mean normalized velocity of circumferential fiber lengthening (VCFL) and left ventricular diastolic distensibility obtained noninvasively from combined recordings of simultaneously calibrated left apex cardiogram and M-mode echogram. Twenty-two normal subjects were similarly investigated and served as a control. In HOCM VCFs were increased (1.83±0.2s-1 versus 1.22±0.1s-1 for controls, p<0.02) and both VGFL and diastolic distensibility were decreased (VCFL: 0.50±0.1s-1 versus 1.32s-1 in controls, p<0.001; diastolic distensibility: 0.03±0.004cm/mmHg-1 compared with 0.18±0.003 cm/mmHg-1 for controls, p<0.001). In COCM all investigated indexes were diminished (VCFs: 0.49+0.1 s-1 versus 1.22±0.1s-1 for controls, p<0.001; VCFL: 0.70±0.1s-1 versus 1.32±0.1s-1 in controls, p<0.01 and diastolic distensibility: 0.05±0.003 cm/mmHg-1 compared with 0.18±0.003 cm/mmHg-1 for controls, p<0.01). The echo-apexcardiographic indexes were significantly correlated with many analogous invasive indexes. It is concluded that the value of both M-mode echocardiography and calibrated apex cardiography is enchanced by a combination of the two methods which opens the possibility of a fresh approach to the noninvasive study of cardiac performance in cardiomyopathy.

Original languageEnglish
Pages (from-to)477-486
Number of pages10
JournalJapanese Heart Journal
Issue number4
Publication statusPublished - Jan 1 1984



  • Cardiomyopathy
  • Echo-apexcardiography Contraction
  • Relaxation

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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