Colocalization of GABA-immunoreactivity in neuropeptide- and monoamine- containing amacrine cells in the retina of Bufo marinus

C. M. Main, M. Wilhelm, R. Gábriel

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Abstract

Immunocytochemical study was performed in the Bufo marinus retina to reveal the localization of γ-aminobutyric acid (GABA)-immunoreactivity in neuropeptide Y (NPY)-, substance P (SP)-, serotonin (5HT)- and tyrosin hydroxylase (TH)-immunoreactive amacrine cells. GABA-immunoreactivity was present in all NPY-, in some of the SP- and 5HT-containing amacrine cells, but not in TH-immunoreactive amacrine cells. Among the 5HT-immunoreactive amacrine cells, a population of 5HT-synthesizing and most of the 5HT- accumulating cells were GABA-immunoreactive. These results indicate that neuropeptide- and GABA-immunoreactivity are colocalized in amacrine cells of the anuran retina. We propose a possible co-transmission for two classical neurotransmitters (GABA and 5HT) in some of the 5HT-containing amacrine cells.

Original languageEnglish
Pages (from-to)161-166
Number of pages6
JournalArchives of Histology and Cytology
Volume56
Issue number2
Publication statusPublished - 1993

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Bufo marinus
Amacrine Cells
Neuropeptides
gamma-Aminobutyric Acid
Retina
Neuropeptide Y
Substance P
Mixed Function Oxygenases
Aminobutyrates
Neurotransmitter Agents
Serotonin
Population

ASJC Scopus subject areas

  • Anatomy
  • Histology

Cite this

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AU - Wilhelm, M.

AU - Gábriel, R.

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