Colloidal stability of carboxylated iron oxide nanomagnets for biomedical use

E. Tombácz, M. Szekeres, Angéla Hajdú, Ildikó Y. Tóth, Rita Andrea Bauer, Dániel Nesztor, E. Illés, I. Zupkó, Ladislau Vékás

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Magnetite nanoparticles (MNP) were synthesized and stabilized with carboxylated compounds citric acid - CA, poly(acrylic acid) - PAA, poly(acrylic acid-co-maleic acid) - PAM, humic acid - HA and gallic acid - GA (polymerizing in situ on the surface). Adsorption isotherms and bonding feature were determined and used to explain the changes in charge and aggregation states and salt tolerance of the MNPs. The thicker layer of macromolecular acids PAA, PAM and HA provides better stability at physiological pH and salt concentration compared to the CA and GA coatings. In addition, Fe(III)-CA complexation promotes the dissolution of the nanoparticles. The biocompatibility of the polyacid-coated MNPs was tested in cell proliferation experiments.

Original languageEnglish
Pages (from-to)3-10
Number of pages8
JournalPeriodica Polytechnica: Chemical Engineering
Volume58
Issue numberSUPPL
DOIs
Publication statusPublished - 2014

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carbopol 940
Pulse amplitude modulation
Iron oxides
Magnetite Nanoparticles
Salts
Humic Substances
Gallic Acid
Acids
Cell proliferation
Complexation
Biocompatibility
Adsorption isotherms
Citric Acid
Dissolution
Agglomeration
Acrylics
Nanoparticles
Coatings
Magnetite nanoparticles
Citric acid

Keywords

  • Adsorption
  • Biocompatibility
  • Carboxylated magnetite nanoparticles
  • Nanoparticle stabilization
  • Overcharging
  • Small and macromolecular organic polyacids

ASJC Scopus subject areas

  • Chemical Engineering(all)

Cite this

Colloidal stability of carboxylated iron oxide nanomagnets for biomedical use. / Tombácz, E.; Szekeres, M.; Hajdú, Angéla; Tóth, Ildikó Y.; Bauer, Rita Andrea; Nesztor, Dániel; Illés, E.; Zupkó, I.; Vékás, Ladislau.

In: Periodica Polytechnica: Chemical Engineering, Vol. 58, No. SUPPL, 2014, p. 3-10.

Research output: Contribution to journalArticle

Tombácz, E. ; Szekeres, M. ; Hajdú, Angéla ; Tóth, Ildikó Y. ; Bauer, Rita Andrea ; Nesztor, Dániel ; Illés, E. ; Zupkó, I. ; Vékás, Ladislau. / Colloidal stability of carboxylated iron oxide nanomagnets for biomedical use. In: Periodica Polytechnica: Chemical Engineering. 2014 ; Vol. 58, No. SUPPL. pp. 3-10.
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AU - Bauer, Rita Andrea

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