Cold-adaptation: Neuropeptide Y versus thermal signals in the development of hyperphagia

Márta Balaskó, Erika Pétervári, Marg Koncsecskó-Gáspár, Miklós Székely

Research output: Contribution to journalArticle

3 Citations (Scopus)


(1) Chronic cold exposure elicited immediate hyperphagia in rats, while the fasting-induced hyperphagia became enhanced after 3 weeks (but not 1 week) of adaptation. (2) The NPY-induced hyperphagia increased quickly with cold-adaptation, even in tests performed outside the cold chamber. (3) Resting core temperature decreased by about 0.4-0.6°C after 3 weeks (full adaptation). (4) Peripheral cold signals rather than NPY appear to be important in the fast development of cold-induced hyperphagia. (5) NPY may play a slowly developing, additional role in this hyperphagia and may contribute to mild hypothermia.

Original languageEnglish
Pages (from-to)115-123
Number of pages9
JournalJournal of Thermal Biology
Issue number1-2 SPEC. ISS.
Publication statusPublished - Jan 1 2006


  • Body temperature
  • Body weight
  • Cold-adaptation
  • Fasting
  • Food intake
  • Metabolic rate
  • Neuropeptide Y

ASJC Scopus subject areas

  • Biochemistry
  • Physiology
  • Agricultural and Biological Sciences(all)
  • Developmental Biology

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