Cohort profile: The european male ageing study

David M. Lee, Stephen R. Pye, Abdelouahid Tajar, Terence W. O'Neill, Joseph D. Finn, Steven Boonen, Gyorgy Bartfai, Felipe F. Casanueva, Gianni Forti, Aleksander Giwercman, Thang S. Han, Ilpo T. Huhtaniemi, Krzysztof Kula, Michael E.J. Lean, Neil Pendleton, Margus Punab, Alan J. Silman, Dirk Vanderschueren, Frederick C.W. Wu

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

The European Male Ageing Study (EMAS) was designed to examine the hypothesis that inter-individual and regional variability in symptomatic dysfunctions, alterations in body composition and health outcomes in ageing men can be explained by different rates of decline in anabolic hormones, the most important of which being testosterone. Between 2003 and 2005, 3369 community- dwelling men, aged between 40 and 79 years, were recruited from population-based registers in eight European centres to participate in the baseline survey, with follow-up investigations performed a median of 4.3 years later. Largely, identical questionnaire instruments and clinical investigations were used in both phases to capture contemporaneous data on general health (including cardiovascular diseases and chronic conditions), physical and cognitive functioning, mental health, sexual function, quality of life, bone health, chronic pain, disease biomarkers, hormones (sex hormones and metabolic hormones) and genetic polymorphisms. EMAS actively encourages new collaborations, data sharing for validation studies and participation in genetic study consortia. Potential collaborators should contact the principal investigator (F.C.W.W.) in the first instance.

Original languageEnglish
Pages (from-to)391-401
Number of pages11
JournalInternational journal of epidemiology
Volume42
Issue number2
DOIs
Publication statusPublished - Apr 1 2013

ASJC Scopus subject areas

  • Epidemiology

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    Lee, D. M., Pye, S. R., Tajar, A., O'Neill, T. W., Finn, J. D., Boonen, S., Bartfai, G., Casanueva, F. F., Forti, G., Giwercman, A., Han, T. S., Huhtaniemi, I. T., Kula, K., Lean, M. E. J., Pendleton, N., Punab, M., Silman, A. J., Vanderschueren, D., & Wu, F. C. W. (2013). Cohort profile: The european male ageing study. International journal of epidemiology, 42(2), 391-401. https://doi.org/10.1093/ije/dyr234