Cochlear implantation for treatment-induced ototoxic deafness in Langerhans cell histiocytosis. A case report

Attila Torkos, Jeno Czigner, József Géza Kiss, Ferenc Tóth, Alice Szamosközi, József Jóri

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A case is presented where the authors carried out a cochlear implantation on a girl whose deafness was induced by cytostatic agents. The normally hearing child was diagnosed with Langerhans cell histiocytosis at the age of 3 years and received polychemotherapy for almost 2 years. By her 5th year, she started to develop a bilateral, progressive sensorineural hearing loss, necessitating a hearing aid in both ears. While her histiocytosis was cured, her hearing ultimately deteriorated to total deafness on the right and profound hearing loss on the left ear. After 3 years, her hearing aids no longer provided adequate hearing for the postlingually deafened girl. At the age of 14, a cochlear implantation was performed on her right ear with excellent results.

Original languageEnglish
Pages (from-to)496-500
Number of pages5
JournalEuropean Archives of Oto-Rhino-Laryngology
Issue number6
Publication statusPublished - Jun 1 2005



  • Chemotherapy
  • Cochlear implantation
  • Histiocytosis
  • Ototoxicity
  • Postlingual deafness

ASJC Scopus subject areas

  • Otorhinolaryngology

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