Co-infections in visceral pentastomiasis, Democratic Republic of the Congo

Dennis Tappe, Mihály Sulyok, Therese Riu, Lajos Rózsa, Imre Bodó, Christoph Schoen, Birgit Muntau, Gergely Babocsay, Richard Hardi

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Snakeborne Armillifer pentastomiasis is an emerging human parasitic infection in rural tropical areas where snake meat is eaten. After a series of severe ocular A. grandis larval infections and anecdotal abdominal infection in Sankuru District, Democratic Republic of the Congo, during 2014-2015, we systematically investigated possible pentastomid etiology in patients who underwent surgery in the region. Histologic and molecular analyses by established pentastomid 18S rDNA-and newly developed Armillifer-specific cytochrome oxidase PCRs revealed larval pentastomid lesions in 3.7% of patients. Some persons had A. armillatus and A. grandis co-infections. Another pentastomid larva, Raillietiella sp., was molecularly detected in 1 patient who had concomitant A. grandis and A. armillatus infection. The PCRs used were suitable for detecting pentastomid species even in highly necrotic tissues. Phylogenetic analyses of Armillifer cytochrome oxidase genes detected multiple local strains.

Original languageEnglish
Pages (from-to)1333-1339
Number of pages7
JournalEmerging Infectious Diseases
Volume22
Issue number8
DOIs
Publication statusPublished - Aug 2016

ASJC Scopus subject areas

  • Epidemiology
  • Microbiology (medical)
  • Infectious Diseases

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    Tappe, D., Sulyok, M., Riu, T., Rózsa, L., Bodó, I., Schoen, C., Muntau, B., Babocsay, G., & Hardi, R. (2016). Co-infections in visceral pentastomiasis, Democratic Republic of the Congo. Emerging Infectious Diseases, 22(8), 1333-1339. https://doi.org/10.3201/eid2208.151895