CNEUPRO: Novel biomarkers for neurodegenerative diseases

Philipp Spitzer, Hans Wolfgang Klafki, Kaj Blennow, Luc Buée, Hermann Esselmann, Sanna Kaisa Herruka, Connie Jimenez, Peter Klivenyi, Piotr Lewczuk, Juan Manuel Maler, Katrin Markus, Helmut E. Meyer, Chris Morris, Thorsten Müller, Markus Otto, Lucilla Parnetti, Hilkka Soininen, Susanna Schraen, Charlotte Teunissen, Laszlo VecseiHenrik Zetterberg, Jens Wiltfang

Research output: Contribution to journalReview article

14 Citations (Scopus)

Abstract

clinical NEUroPROteomics of neurodegenerative diseases (cNEUPRO) is a Specific Targeted Research Project (STREP) within the sixth framework program of the European Commission dedicated to the search for novel biomarker candidates for Alzheimer's disease and other neurodegenerative diseases. The ultimate goal of cNEUPRO is to identify one or more valid biomarker(s) in blood and CSF applicable to support the early and differential diagnosis of dementia disorders. The consortium covers all steps required for the discovery of novel biomarker candidates such as acquisition of high quality CSF and blood samples from relevant patient groups and controls, analysis of body fluids by various methods, and finally assay development and assay validation. Here we report the standardized procedures for diagnosis and preanalytical sample-handling within the project, as well as the status of the ongoing research activities and some first results.

Original languageEnglish
Article number548145
JournalInternational Journal of Alzheimer's Disease
DOIs
Publication statusPublished - 2010

ASJC Scopus subject areas

  • Ageing
  • Neurology
  • Clinical Neurology
  • Cognitive Neuroscience
  • Cellular and Molecular Neuroscience
  • Behavioral Neuroscience

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    Spitzer, P., Klafki, H. W., Blennow, K., Buée, L., Esselmann, H., Herruka, S. K., Jimenez, C., Klivenyi, P., Lewczuk, P., Maler, J. M., Markus, K., Meyer, H. E., Morris, C., Müller, T., Otto, M., Parnetti, L., Soininen, H., Schraen, S., Teunissen, C., ... Wiltfang, J. (2010). CNEUPRO: Novel biomarkers for neurodegenerative diseases. International Journal of Alzheimer's Disease, [548145]. https://doi.org/10.4061/2010/548145