A Clostridium difficile-fertozések epidemiológiája, betegségterhe és terápiája

Translated title of the contribution: Clostridium difficile infection: epidemiology, disease burden and therapy

László Gulácsi, Adrienne Kertész, Irén Kopcsóné Németh, János Banai, Endre Ludwig, Gyula Prinz, Péter Reményi, Bálint Strbák, Edit Zsoldiné Urbán, Petra Baji, Márta Péntek, Valentin Brodszky

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Introduction:C. difficile causes 25 percent of the antibiotic associated infectious nosocomial diarrhoeas. C. difficile infection is a high-priority problem of public health in each country. The available literature of C. difficile infection's epidemiology and disease burden is limited. Aim: Review of the epidemiology, including seasonality and the risk of recurrences, of the disease burden and of the therapy of C. difficile infection. Method: Review of the international and Hungarian literature in MEDLINE database using PubMed up to and including 20th of March, 2012. Results: The incidence of nosocomial C. difficile associated diarrhoea is 4.1/10 000 patient day. The seasonality of C. difficile infection is unproved. 20 percent of the patients have recurrence after metronidazole or vancomycin treatment, and each recurrence increases the chance of a further one. The cost of C. difficile infection is between 130 and 500 thousand HUF (430 and 1665) in Hungary. Conclusions: The importance of C. difficile infection in public health and the associated disease burden are significant. The available data in Hungary are limited, further studies in epidemiology and health economics are required.

Translated title of the contributionClostridium difficile infection: epidemiology, disease burden and therapy
Original languageHungarian
Pages (from-to)1188-1193
Number of pages6
JournalOrvosi hetilap
Volume154
Issue number30
DOIs
Publication statusPublished - Jul 1 2013

ASJC Scopus subject areas

  • Medicine(all)

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  • Cite this

    Gulácsi, L., Kertész, A., Kopcsóné Németh, I., Banai, J., Ludwig, E., Prinz, G., Reményi, P., Strbák, B., Urbán, E. Z., Baji, P., Péntek, M., & Brodszky, V. (2013). A Clostridium difficile-fertozések epidemiológiája, betegségterhe és terápiája. Orvosi hetilap, 154(30), 1188-1193. https://doi.org/10.1556/OH.2013.29674