A fokális dystoniák tünettana, diagnosztikája és kezelése.

Translated title of the contribution: Clinical symptoms, diagnosis and treatment of focal dystonias

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Focal dystonias are relatively rare and significantly disabling disorders. These include cervical dystonia, blepharospasm and hemifacial spasm. The spasmodic torticollis consists of tonic posturing of the head away from its neutral position or twisting of the cervical muscles. The blepharospasm is an abnormal blinking, eyelid tic or twitch resulting from any cause. The hemifacial spasm is an involuntary unilateral twitching of the facial muscle. Patients affected by focal dystonias are predominantly females, and many times psychical stress can be revealed. The pathogenesis may involve dysfunction of the basal ganglia and brain stem although the exact mechanism remains to be elucidated. The patients need to be diagnosed and treated in centers specialized in movement disorders. Although many drug treatments can be beneficial, the most effective treatment is the local Botulinum toxin injection into the affected muscles. This neurotoxin produces temporary neuromuscular blockade, which reveals the symptoms and pain. The effect of the toxin is temporary and, therefore, the injection needs to be repeated every 6-12 weeks. The most common side effects are hypersensitivity, bleeding, hematoma, ptosis, facial spasm, dysphasia or dysarthria. With the use of proper dose and injection sites these side effects can be avoided.

Original languageHungarian
Pages (from-to)2293-2297
Number of pages5
JournalOrvosi Hetilap
Volume142
Issue number42
Publication statusPublished - Oct 21 2001

Fingerprint

Dystonic Disorders
Blepharospasm
Hemifacial Spasm
Torticollis
Injections
Facial Muscles
Blinking
Tics
Dysarthria
Muscles
Neuromuscular Blockade
Botulinum Toxins
Aphasia
Neurotoxins
Movement Disorders
Spasm
Eyelids
Basal Ganglia
Hematoma
Brain Stem

ASJC Scopus subject areas

  • Medicine(all)

Cite this

A fokális dystoniák tünettana, diagnosztikája és kezelése. / Klivényi, P.; Vécsei, L.

In: Orvosi Hetilap, Vol. 142, No. 42, 21.10.2001, p. 2293-2297.

Research output: Contribution to journalArticle

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