Szérum thyreoglobulin és thyreoglobulinellenes antitest meghatározásának klinikai jelentôsége pajzsmirigyrákkal mûtött betegek vizsgálata során.

Translated title of the contribution: Clinical significance of serum thyroglobulin and antithyroglobulin antibody in differentiated thyroid cancer after thyroid ablation

Borbála Vincze, István Sinkovics, Sándor Keresztes, Mária Gergye, András Boér, Eva Remenár, Ilona Péter, Zoltán Szentirmay, Tibor Kremmer, Kásler Miklsó

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Serum thyroglobulin (Tg) is a suitable marker for differentiated thyroid carcinoma following total thyroid ablation. Between 1998 and 2003, serum samples from 715 papillary and 179 follicular tumor patients treated with total/nearly total thyroidectomy and radioiodine ablation therapy were collected. According to the "Guidelines for Oncotherapy in Hungary", serum Tg, antithyroglobulin antibody (TgAb), TSH and FT4 levels were measured in periods of 3 months following the first treatment and of 6 months after 2 years. In the present work the prognostic value of Tg and TgAb data of cancer patients with hormone substitution therapy were evaluated individually and retrospectively. Serum Tg and TgAb concentrations were measured with a highly sensitive immunoradiometric (IRMA) method, and with a second generation, broad epitope specificity competitive radioimmunoassay, respectively. TSH levels determined by fourth generation LIAISON kit were in a range of 0.05-0.10 mIU/L. Accuracy of measuring of Tg

Translated title of the contributionClinical significance of serum thyroglobulin and antithyroglobulin antibody in differentiated thyroid cancer after thyroid ablation
Original languageHungarian
Pages (from-to)27-34
Number of pages8
JournalMagyar Onkologia
Volume48
Issue number1
Publication statusPublished - 2004

ASJC Scopus subject areas

  • Cancer Research

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