Clinical importance of antiplatelet drugs in cardiovascular diseases

J. Papp, P. Kenyeres, K. Tóth

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Platelets play an important role both in normal hemostasis and in pathological thrombus formation. Several large-scale clinical studies have proved that the inhibition of platelet aggregation results in a significant decrease in mortality and morbidity of ischemic atherothrombotic events, thus antiplatelet therapy became a key pharmacological method in prevention and treatment of such cardiovascular, cerebrovascular and peripheral arterial diseases. The present paper aims to give a brief overview of the most important antiplatelet drugs, their mechanism of action and their recommended usage in cardiovascular diseases. We also discuss possible methods to monitor the effectiveness of therapy and possible causes of therapeutic failure.

Original languageEnglish
Pages (from-to)81-96
Number of pages16
JournalClinical Hemorheology and Microcirculation
Volume53
Issue number1-2
DOIs
Publication statusPublished - 2013

Fingerprint

Platelet Aggregation Inhibitors
Cardiovascular Diseases
Peripheral Arterial Disease
Hemostasis
Platelet Aggregation
Thrombosis
Therapeutics
Blood Platelets
Pharmacology
Morbidity
Mortality

Keywords

  • Antiplatelet drugs
  • aspirin and clopidogrel resistance
  • coronary heart disease
  • inhibition of platelet aggregation
  • peripheral arterial disease
  • platelet aggregometry
  • stroke

ASJC Scopus subject areas

  • Hematology
  • Physiology
  • Physiology (medical)
  • Cardiology and Cardiovascular Medicine

Cite this

Clinical importance of antiplatelet drugs in cardiovascular diseases. / Papp, J.; Kenyeres, P.; Tóth, K.

In: Clinical Hemorheology and Microcirculation, Vol. 53, No. 1-2, 2013, p. 81-96.

Research output: Contribution to journalArticle

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