Demography, morbidity, perioperative characteristics and mortality. Introduction: The authors summarize the demographic, morbidity and mortality characteristics of the Hungarian Liver Transplant Program. They evaluate the changes and development, that has taken place with regard to indications, recipient population and characteristics, operation technique, and peroperative patient management. Method: In order to present the development, data are compared between two time periods (before and after 1999). Categorical variables are evaluated by chisquare test, continuous ones are with Levene Test (for homogeneicity of means), Student T test and Mann-Whitney U-test. Cumulative survivals are computed with Kaplan-Meyer log rank analysis. Variables showed statistical significance on survival bz univariate analysis were then put into multivariate Cox-regression analysis. ROC analysis was performed to set the cut off point of certain continuous parameters in relation to survival. Results: The results are summarized on Tables and statistical Figures. Regarding patients mortality in the beginning the main factors with impact were respectively technical ones like arterial thrombosis, while in the last 4 years perioperative fluid management and transfusion policy became important. Both sepsis and posztoperative renal insufficiency remained key factors for mortality, however their incidence diminished dramatically. Discussion: The overall outcome of the retrospective analysis is, that the program has been developed to European standards with respect to its volume, technical capabilities and results.
|Number of pages||8|
|Publication status||Published - Dec 1 2005|
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