The authors give an overview of the etiology, pathogenesis and clinical findings of botulism in horses in connection with a clinical case describing the disease in a three-year-old, castrated horse. The animal was taken to the hospital 36 hours after the appearance of the first clinical signs, colic symptoms, swallowing disorder and ataxia. Main clinical signs in the following included colic symptoms, medium-level dehydration, slight cyanosis on the mucous membrane of the lips, medium-level mixed-type dyspnoea, tachycardia, atonic tongue, missing intestinal sounds and symmetric muscular tremor in the region of the scapula and the shoulder on both sides. Consciousness was not impaired. In standing position the horse was staggering in straddle position and during walking the front limbs also showed ataxic symptoms. The horse tried to pick up some oat but it fell out from its mouth and when it tried to drink it couldn't forward the water to its oral cavity. During rectal examination a full, atonic urinary bladder was found. With nasogastric tube we gained 6 liters of stenchy brownish yellow gastric content which had a pH value of 8. The laboratory examination of the blood revealed increased packed cell volume and decreased white blood cell number. The AST-, lipase- and CK-activities of the plasma increased and the albumin-concentration decreased. We found some protein and bilirubin in the urine. The state of the patient became worse in spite of immediate intensive therapy, therefore euthanasia was applied 2 hours after arrival. The pathological examination found focal encephalomalacia in the white matter of the cerebellum, bleedings in the medulla oblongata and severe pulmonary edema. The examination of the brain for rabies was negative. We detected Clostridium botulinum toxin in the patient's serum with mouse bio-assay (intraperitoneal injection).
|Translated title of the contribution||Clinical diagnosis of botulism in a horse. Case report|
|Number of pages||5|
|Journal||Magyar Allatorvosok Lapja|
|Publication status||Published - Dec 1 2000|
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