Fertilis korú nok hepatitis C-vírus-fertozésének klinikai vonatkozásai

Translated title of the contribution: Clinical aspects of hepatitis C virus infection in child-bearing aged women

Béla Lombay, B. Gasztonyi, F. Szalay

Research output: Contribution to journalArticle

Abstract

It is difficult to define the optimal timing of antiviral treatment in women infected with viral hepatitis C, who have child-bearing potential. Antiviral treatment is strictly contraindicated during pregnancy and The breast-feeding period. Data are conflicting about the question of treatment with modern drugs (peginterferon and ribavirin) before or after pregnancy. The risk of vertical transmission from mother to child is estimated about 5%. The mother's viraemia seems to be the main transmission factor. There is a worse prognosis in nulliparous and postmenopausal women in the natural history of viral hepatitis C. Poor outcome in gestational age, maturity and Apgar score were not associated with hepatitis C virus infection. Combined treatment has frequent gynecological and other side effects. The timing of antiviral therapy in women in child-bearing period is recommended individually.

Original languageHungarian
Pages (from-to)1017-1021
Number of pages5
JournalOrvosi Hetilap
Volume149
Issue number22
DOIs
Publication statusPublished - Jun 1 2008

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Virus Diseases
Hepacivirus
Antiviral Agents
Hepatitis C
Mothers
Therapeutics
Pregnancy
Apgar Score
Ribavirin
Viremia
Breast Feeding
Natural History
Gestational Age
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Fertilis korú nok hepatitis C-vírus-fertozésének klinikai vonatkozásai. / Lombay, Béla; Gasztonyi, B.; Szalay, F.

In: Orvosi Hetilap, Vol. 149, No. 22, 01.06.2008, p. 1017-1021.

Research output: Contribution to journalArticle

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