Abstract
The clinical applications of GnRH and its analogues are discussed. GnRH can be used diagnostically to assess the releasable pool of LH and the status of gonadotrophin secretion. Clinically it can be used to induce follicle growth and ovulation In patients with hypogonadotrophic ajnenorrhoea, especially when given in pulsatile form, and there are reports that it might also stimulate spermatogenesis in men with hypogonadotrophic hypogonadism. Analogues are proving valuable in the treatment of precocious puberty, but are not yet practical for contraception. They are more valuable in the treatment of endometriosis, hormone-dependent cancers, the polycystic ovary and for the induction of ovulation for In-vitro fertilization.
| Original language | English |
|---|---|
| Pages (from-to) | 51-57 |
| Number of pages | 7 |
| Journal | Human Reproduction |
| Volume | 3 |
| Issue number | 1 |
| Publication status | Published - Jan 1988 |
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Keywords
- Gonadotrophin-hormone releasing hormones
- Gonadotrophins
- Human reproductive endocrinology
ASJC Scopus subject areas
- Statistics, Probability and Uncertainty
- Applied Mathematics
- Physiology (medical)
- Reproductive Medicine
- Obstetrics and Gynaecology
- Rehabilitation
- Developmental Biology
- Physiology
Cite this
Clinical applications of gonadotrophin-releasing hormone and its analogues. / Bártfai, G.
In: Human Reproduction, Vol. 3, No. 1, 01.1988, p. 51-57.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Clinical applications of gonadotrophin-releasing hormone and its analogues
AU - Bártfai, G.
PY - 1988/1
Y1 - 1988/1
N2 - The clinical applications of GnRH and its analogues are discussed. GnRH can be used diagnostically to assess the releasable pool of LH and the status of gonadotrophin secretion. Clinically it can be used to induce follicle growth and ovulation In patients with hypogonadotrophic ajnenorrhoea, especially when given in pulsatile form, and there are reports that it might also stimulate spermatogenesis in men with hypogonadotrophic hypogonadism. Analogues are proving valuable in the treatment of precocious puberty, but are not yet practical for contraception. They are more valuable in the treatment of endometriosis, hormone-dependent cancers, the polycystic ovary and for the induction of ovulation for In-vitro fertilization.
AB - The clinical applications of GnRH and its analogues are discussed. GnRH can be used diagnostically to assess the releasable pool of LH and the status of gonadotrophin secretion. Clinically it can be used to induce follicle growth and ovulation In patients with hypogonadotrophic ajnenorrhoea, especially when given in pulsatile form, and there are reports that it might also stimulate spermatogenesis in men with hypogonadotrophic hypogonadism. Analogues are proving valuable in the treatment of precocious puberty, but are not yet practical for contraception. They are more valuable in the treatment of endometriosis, hormone-dependent cancers, the polycystic ovary and for the induction of ovulation for In-vitro fertilization.
KW - Gonadotrophin-hormone releasing hormones
KW - Gonadotrophins
KW - Human reproductive endocrinology
UR - http://www.scopus.com/inward/record.url?scp=0023845994&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0023845994&partnerID=8YFLogxK
M3 - Article
C2 - 3280595
AN - SCOPUS:0023845994
VL - 3
SP - 51
EP - 57
JO - Human Reproduction
JF - Human Reproduction
SN - 0268-1161
IS - 1
ER -