Clinical applications of gonadotrophin-releasing hormone and its analogues

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The clinical applications of GnRH and its analogues are discussed. GnRH can be used diagnostically to assess the releasable pool of LH and the status of gonadotrophin secretion. Clinically it can be used to induce follicle growth and ovulation In patients with hypogonadotrophic ajnenorrhoea, especially when given in pulsatile form, and there are reports that it might also stimulate spermatogenesis in men with hypogonadotrophic hypogonadism. Analogues are proving valuable in the treatment of precocious puberty, but are not yet practical for contraception. They are more valuable in the treatment of endometriosis, hormone-dependent cancers, the polycystic ovary and for the induction of ovulation for In-vitro fertilization.

Original languageEnglish
Pages (from-to)51-57
Number of pages7
JournalHuman Reproduction
Volume3
Issue number1
Publication statusPublished - Jan 1988

Fingerprint

Ovulation
Gonadotropins
Hormones
Gonadotropin-Releasing Hormone
Endometriosis
Analogue
Precocious Puberty
In Vitro Fertilization
Ovary
Hypogonadism
Ovulation Induction
Secretion
Spermatogenesis
Fertilization in Vitro
Contraception
Ovarian Neoplasms
Proof by induction
Cancer
Dependent
Therapeutics

Keywords

  • Gonadotrophin-hormone releasing hormones
  • Gonadotrophins
  • Human reproductive endocrinology

ASJC Scopus subject areas

  • Statistics, Probability and Uncertainty
  • Applied Mathematics
  • Physiology (medical)
  • Reproductive Medicine
  • Obstetrics and Gynaecology
  • Rehabilitation
  • Developmental Biology
  • Physiology

Cite this

Clinical applications of gonadotrophin-releasing hormone and its analogues. / Bártfai, G.

In: Human Reproduction, Vol. 3, No. 1, 01.1988, p. 51-57.

Research output: Contribution to journalArticle

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