Indukált és spontán köpet klinikai felhasználása asztmában és krónikus obstruktív tüdobetegségben.

Translated title of the contribution: [Clinical application of induced and spontaneous sputum in asthma and chronic obstructive pulmonary disease].

Research output: Contribution to journalReview article

2 Citations (Scopus)


In recent years induced sputum analysis has become a non-invasive method for the assessment of airway inflammation in obstructive airway diseases. Sputum induction is safe and well tolerated by the patients. The method has been standardized, and this has markedly improved the quality and reproducibility of sputum samples. Identification of sputum eosinophilia has the greatest clinical relevance as it predicts a favorable response to corticosteroids. Treatment strategy aiming normalisation of sputum eosinophil cell count may reduce the rate of exacerbations in asthma. Profiling inflammatory mediators in sputum supernatant provides new insights into the pathogenesis of asthma and chronic obstructive pulmonary disease. Cell type analysis in spontaneous sputum may also provide much information about inflammatory processes in the airways. Based on the results of clinical studies sputum analysis should be more often used in clinical settings in the future.

Original languageHungarian
Pages (from-to)1847-1854
Number of pages8
JournalOrvosi hetilap
Issue number47
Publication statusPublished - Nov 25 2012


ASJC Scopus subject areas

  • Medicine(all)

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