Clinical and histological evaluation of synovial needle-biopsies in rheumatoid arthritis. II. Relationship between local clinical activity and histological pattern.

M. Bély, I. Ratkó, L. Hodinka, I. Márkus, D. Tanka, S. Bozsóky

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The histological pattern of synovial needle-biopsies of 50 patients suffering from classical or definitive rheumatoid arthritis has been compared with the clinical activity of the disease. Each histological change was evaluated in terms of its value in characterizing local clinical activity. It was shown that most changes of the synovial ground tissue are in a positive correlation with local clinical activity. Among the vascular changes of the synovial membrane, oedema of vascular walls, exudation of fresh fibrin, leukocyte infiltration and thickening of vascular walls were in negative correlation, while chronic fibrin, lymphocytic or plasma cell infiltration and hyalinosis were in positive correlation with local clinical activity.

Original languageEnglish
Pages (from-to)133-142
Number of pages10
JournalActa Morphologica Hungarica
Volume32
Issue number2
Publication statusPublished - 1984

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Needle Biopsy
Blood Vessels
Rheumatoid Arthritis
Fibrin
Synovial Membrane
Plasma Cells
Edema
Leukocytes

ASJC Scopus subject areas

  • Anatomy

Cite this

Clinical and histological evaluation of synovial needle-biopsies in rheumatoid arthritis. II. Relationship between local clinical activity and histological pattern. / Bély, M.; Ratkó, I.; Hodinka, L.; Márkus, I.; Tanka, D.; Bozsóky, S.

In: Acta Morphologica Hungarica, Vol. 32, No. 2, 1984, p. 133-142.

Research output: Contribution to journalArticle

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AU - Tanka, D.

AU - Bozsóky, S.

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