Citrate enzyme substrates and inhibitors: Depiction of their absolute configurations

Jenny Pickworth Glusker, P. Srere

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

The absolute configurations of the four isomers of hydroxycitric, fluorocitric, and isocitric acids are tabulated and correlations with their interactions with some citrate enzymes are made. In order to facilitate the description of the absolute configurations of related compounds that are interacting with a given enzyme, a local numbering system, in which the compound is related to its parent compound (parent numbering), is suggested.

Original languageEnglish
Pages (from-to)301-310
Number of pages10
JournalBioorganic Chemistry
Volume2
Issue number4
DOIs
Publication statusPublished - 1973

Fingerprint

Enzyme Inhibitors
Citric Acid
Numbering systems
Substrates
Enzymes
Isomers
isocitric acid
hydroxycitric acid

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Organic Chemistry
  • Drug Discovery

Cite this

Citrate enzyme substrates and inhibitors : Depiction of their absolute configurations. / Glusker, Jenny Pickworth; Srere, P.

In: Bioorganic Chemistry, Vol. 2, No. 4, 1973, p. 301-310.

Research output: Contribution to journalArticle

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