cis-2-aminocyclopentanecarboxylic acid oligomers adopt a sheetlike structure: Switch from helix to nonpolar strand

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116 Citations (Scopus)

Abstract

Rational control over helix and strand secondary structures is possible when conformationally restricted cyclic β-amino acid residues are incorporated in the β-peptides. Inversion of the relative configuration of these residues enables the preferred periodic structure to be switched from a helix to a single nonpolar strand (see picture).

Original languageEnglish
Pages (from-to)1718-1721
Number of pages4
JournalAngewandte Chemie - International Edition
Volume41
Issue number10
DOIs
Publication statusPublished - Jun 8 2002

Keywords

  • Amino acids
  • Chirality
  • Conformation analysis
  • NMR spectroscopy
  • Peptides

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

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