Circulating microRNAs in adrenal tumors

Research output: Contribution to journalReview article

2 Citations (Scopus)

Abstract

Purpose of reviewCirculating microRNAs represent promising minimally invasive markers of several diseases including tumors. As the preoperative diagnosis of different adrenal tumors is difficult, for example, diagnosis of adrenocortical or adrenomedullary malignancy, circulating microRNAs might be helpful in their clinical management.Recent findingsObservations regarding the applicability of circulating microRNAs isolated both from unfractionated plasma or serum and from extracellular vesicle preparations for the diagnosis of adrenocortical malignancy have been published. Data show that circulating microRNA might be exploited for monitoring adrenocortical cancer progression. Circulating microRNA profiles of adrenal myelolipoma have also been published that might be useful for differentiating adrenocortical cancer and adrenal myelolipoma in dubious cases.SummaryIn this review, recent advances in the field of circulating microRNAs in adrenal tumors are discussed.

Original languageEnglish
Pages (from-to)155-159
Number of pages5
JournalCurrent Opinion in Endocrinology, Diabetes and Obesity
Volume26
Issue number3
DOIs
Publication statusPublished - Jun 1 2019

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Keywords

  • adenoma
  • adrenocortical
  • cancer
  • circulating
  • microRNA
  • myelolipoma
  • pheochromocytoma

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Endocrinology
  • Nutrition and Dietetics

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