Circulating ICAM-1 in alcoholic liver cirrhosis

Y. Mándi, I. Nagy

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

The intercellular adhesion molecule 1 (ICAM-1) level in the serum o f patients with alcoholic liver cirrhosis was measured using a sandwich enzyme-linked immunosorbentassay. Circulating ICAM-1 was significantly elevated in the sera o f all 19 patients as compared with normal healthy subjects. There was no correlation with the Child grade o f the disease, but the highest levels o f serum ICAM-1(2,416 5 6 0 ng/ml) were measured in those patients who sufferred from superimposed acute alcoholic hepatitis. No elevated serum ICAM-1 level was found in the ascitic fluid o f cirrhotic patients. The elevated serum levels o f ICAM-1 in patients with alcoholic liver diseases may provide useful diagnostic or prognostic information.

Original languageEnglish
Pages (from-to)302-304
Number of pages3
JournalInternational Archives of Allergy and Immunology
Volume106
Issue number3
DOIs
Publication statusPublished - 1995

Fingerprint

Alcoholic Liver Cirrhosis
Intercellular Adhesion Molecule-1
Serum
Alcoholic Hepatitis
Alcoholic Liver Diseases
Ascitic Fluid
Healthy Volunteers
Enzymes

Keywords

  • Alcoholic liver cirrhosis
  • Intercellular adhesion molecule 1
  • Sepsis

ASJC Scopus subject areas

  • Immunology
  • Immunology and Allergy

Cite this

Circulating ICAM-1 in alcoholic liver cirrhosis. / Mándi, Y.; Nagy, I.

In: International Archives of Allergy and Immunology, Vol. 106, No. 3, 1995, p. 302-304.

Research output: Contribution to journalArticle

@article{efee76e6b62c497293c1558e773c7b33,
title = "Circulating ICAM-1 in alcoholic liver cirrhosis",
abstract = "The intercellular adhesion molecule 1 (ICAM-1) level in the serum o f patients with alcoholic liver cirrhosis was measured using a sandwich enzyme-linked immunosorbentassay. Circulating ICAM-1 was significantly elevated in the sera o f all 19 patients as compared with normal healthy subjects. There was no correlation with the Child grade o f the disease, but the highest levels o f serum ICAM-1(2,416 5 6 0 ng/ml) were measured in those patients who sufferred from superimposed acute alcoholic hepatitis. No elevated serum ICAM-1 level was found in the ascitic fluid o f cirrhotic patients. The elevated serum levels o f ICAM-1 in patients with alcoholic liver diseases may provide useful diagnostic or prognostic information.",
keywords = "Alcoholic liver cirrhosis, Intercellular adhesion molecule 1, Sepsis",
author = "Y. M{\'a}ndi and I. Nagy",
year = "1995",
doi = "10.1159/000236859",
language = "English",
volume = "106",
pages = "302--304",
journal = "International Archives of Allergy and Immunology",
issn = "1018-2438",
publisher = "S. Karger AG",
number = "3",

}

TY - JOUR

T1 - Circulating ICAM-1 in alcoholic liver cirrhosis

AU - Mándi, Y.

AU - Nagy, I.

PY - 1995

Y1 - 1995

N2 - The intercellular adhesion molecule 1 (ICAM-1) level in the serum o f patients with alcoholic liver cirrhosis was measured using a sandwich enzyme-linked immunosorbentassay. Circulating ICAM-1 was significantly elevated in the sera o f all 19 patients as compared with normal healthy subjects. There was no correlation with the Child grade o f the disease, but the highest levels o f serum ICAM-1(2,416 5 6 0 ng/ml) were measured in those patients who sufferred from superimposed acute alcoholic hepatitis. No elevated serum ICAM-1 level was found in the ascitic fluid o f cirrhotic patients. The elevated serum levels o f ICAM-1 in patients with alcoholic liver diseases may provide useful diagnostic or prognostic information.

AB - The intercellular adhesion molecule 1 (ICAM-1) level in the serum o f patients with alcoholic liver cirrhosis was measured using a sandwich enzyme-linked immunosorbentassay. Circulating ICAM-1 was significantly elevated in the sera o f all 19 patients as compared with normal healthy subjects. There was no correlation with the Child grade o f the disease, but the highest levels o f serum ICAM-1(2,416 5 6 0 ng/ml) were measured in those patients who sufferred from superimposed acute alcoholic hepatitis. No elevated serum ICAM-1 level was found in the ascitic fluid o f cirrhotic patients. The elevated serum levels o f ICAM-1 in patients with alcoholic liver diseases may provide useful diagnostic or prognostic information.

KW - Alcoholic liver cirrhosis

KW - Intercellular adhesion molecule 1

KW - Sepsis

UR - http://www.scopus.com/inward/record.url?scp=0028966884&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028966884&partnerID=8YFLogxK

U2 - 10.1159/000236859

DO - 10.1159/000236859

M3 - Article

C2 - 7888794

AN - SCOPUS:0028966884

VL - 106

SP - 302

EP - 304

JO - International Archives of Allergy and Immunology

JF - International Archives of Allergy and Immunology

SN - 1018-2438

IS - 3

ER -