A cirkuláris ribonukleinsav és tumorbiológiai jelentosége

Translated title of the contribution: Circular ribonucleic acid and its tumor-biological relevance

Turai Péter István, Igaz Péter

Research output: Contribution to journalArticle

Abstract

One of the most remarkable chapters in recent years' research of molecular biology is the quest for non-coding ribonucleic acids (RNAs). Circular RNAs form a distinct group within non-coding RNAs and their significance is being discovered only now. These uncommonly stable molecules take part in the regulation of gene expression by various mechanisms, e.g., by decoying microRNAs or by acting upon the translational machinery. The altered expression of circular RNAs was described in different types of cancers, and considering their stability, circular RNAs could be exploited as future biomarkers and even as molecular targets. In this synopsis, the authors present the biological characteristics and the tumor-biological relevance of circular RNAs.

Original languageHungarian
Pages (from-to)403-412
Number of pages10
JournalOrvosi hetilap
Volume161
Issue number11
DOIs
Publication statusPublished - Jan 1 2020

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ASJC Scopus subject areas

  • Medicine(all)

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