Chromosome studies on persons suffering from acute phosphate ester (pesticide) poisoning (Hungarian)

Van Bao Trinh Van Bao, I. Szabo, P. Ruzicska, E. Czeizel

Research output: Contribution to journalArticle

Abstract

Chromosome examinations were performed in the peripheral blood culture of patients suffering from grave acute organic phosphoric acid ester (pesticide) poisoning, during the period of intoxication, 1 month and 6 months later. The rate of chromatid breaks acentric fragments and stable chromosome type disorders (deletions, translocations) was found to be significantly high during the intoxication and 1 month later. No definite correlation was found between the frequency of chromosomal disorders and the severity of clinical manifestations. Chromosomal aberrations were most frequent in 'Foszfotion' poisoned persons. The results indicate that the development of chromosome aberrations must be taken into consideration in severe human poisoning caused by phosphoric acid esters. (25 references.)

Original languageEnglish
Pages (from-to)348-360
Number of pages13
JournalEGESZSEGTUDOMANY
Volume18
Issue number4
Publication statusPublished - Jan 1 1974

ASJC Scopus subject areas

  • Medicine(all)

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