Chromatographic properties of s-triazines in the presence of soluble β-cyclodextrin polymer

Tibor Cserháti, Barna Bordás, Éva Fenyvesi, József Szejtli

Research output: Contribution to journalArticle

25 Citations (Scopus)


The effect of a water-soluble β-cyclodextrin polymer on the lipophilicity and adsorption strength of 17 substituted s-triazine derivatives was studied by thin-layer chromatography. Beta-cyclodextrin polymer dissolved in the mobile phase modifies the chromatographic behaviour of s-triazine derivatives and, consequently, higher Rf and lower RM values were observed. LiCl exerts an opposite influence, it decreases the Rf and increases the RM values. The β-cyclodextrin polymer enhances the mobility of the s-triazine derivatives on silica gel and reduces their lipophilicity, thus promoting their penetration through the hydrophilic membranes of the target organism. The presence of LiCl decreases the stability of inclusion complexes. The first and second substituents on the s-triazine ring result in an increase of the inclusion complex stability but - due to steric hindrances - the third substituent decreases it.

Original languageEnglish
Pages (from-to)53-59
Number of pages7
JournalJournal of Inclusion Phenomena
Issue number1
Publication statusPublished - Mar 1 1983


  • thin-layer chromatography
  • triazines
  • β-cyclodextrin polymer

ASJC Scopus subject areas

  • Food Science
  • Chemistry(all)
  • Condensed Matter Physics

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