Chromatographic properties of s-triazines in the presence of soluble β-cyclodextrin polymer

T. Cserháti, Barna Bordás, Éva Fenyvesi, József Szejtli

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

The effect of a water-soluble β-cyclodextrin polymer on the lipophilicity and adsorption strength of 17 substituted s-triazine derivatives was studied by thin-layer chromatography. Beta-cyclodextrin polymer dissolved in the mobile phase modifies the chromatographic behaviour of s-triazine derivatives and, consequently, higher Rf and lower RM values were observed. LiCl exerts an opposite influence, it decreases the Rf and increases the RM values. The β-cyclodextrin polymer enhances the mobility of the s-triazine derivatives on silica gel and reduces their lipophilicity, thus promoting their penetration through the hydrophilic membranes of the target organism. The presence of LiCl decreases the stability of inclusion complexes. The first and second substituents on the s-triazine ring result in an increase of the inclusion complex stability but - due to steric hindrances - the third substituent decreases it.

Original languageEnglish
Pages (from-to)53-59
Number of pages7
JournalJournal of Inclusion Phenomena
Volume1
Issue number1
DOIs
Publication statusPublished - Mar 1983

Fingerprint

Triazines
cyclodextrins
triazines
polymers
chemical derivatives
hydrophobicity
Derivatives
inclusions
thin layer chromatography
silica gel
organisms
Thin layer chromatography
beta-cyclodextrin
Silica Gel
penetration
Thin Layer Chromatography
Adsorption
membranes
Polymers
adsorption

Keywords

  • β-cyclodextrin polymer
  • thin-layer chromatography
  • triazines

ASJC Scopus subject areas

  • Condensed Matter Physics
  • Chemistry(all)

Cite this

Chromatographic properties of s-triazines in the presence of soluble β-cyclodextrin polymer. / Cserháti, T.; Bordás, Barna; Fenyvesi, Éva; Szejtli, József.

In: Journal of Inclusion Phenomena, Vol. 1, No. 1, 03.1983, p. 53-59.

Research output: Contribution to journalArticle

Cserháti, T. ; Bordás, Barna ; Fenyvesi, Éva ; Szejtli, József. / Chromatographic properties of s-triazines in the presence of soluble β-cyclodextrin polymer. In: Journal of Inclusion Phenomena. 1983 ; Vol. 1, No. 1. pp. 53-59.
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