Chromatographic behavior of silica-polymer composite molecularly imprinted materials

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Molecularly imprinted polymers (MIP) have recently been prepared inside the pores of silica based HPLC packing materials. Detailed physical and chromatographic characterization of such a silica-MIP composite material is presented. The chromatographic peak shape obtained with the uniformly sized spherical silica-MIP composite is mainly determined by the nonlinear adsorption isotherm. Comparison of the composite with the conventional sieved and grinded bulk MIP is therefore based on the nonlinear isotherm and not on retention factors and plate numbers.

Original languageEnglish
Pages (from-to)60-67
Number of pages8
JournalJournal of Chromatography A
Volume1100
Issue number1
DOIs
Publication statusPublished - Dec 23 2005

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Silicon Dioxide
Polymers
Composite materials
Adsorption isotherms
Adsorption
Isotherms
High Pressure Liquid Chromatography

Keywords

  • Composite
  • HPLC
  • Imprinted polymer
  • Nonlinear

ASJC Scopus subject areas

  • Analytical Chemistry

Cite this

Chromatographic behavior of silica-polymer composite molecularly imprinted materials. / Tóth, B.; László, K.; Horvai, G.

In: Journal of Chromatography A, Vol. 1100, No. 1, 23.12.2005, p. 60-67.

Research output: Contribution to journalArticle

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