Cholinergic synapses in the rat brain: a correlated light and electron microscopic immunohistochemical study employing a monoclonal antibody against choline acetyltransferase

B. H. Wainer, J. P. Bolam, T. Freund, Z. Henderson, S. Totterdell, A. D. Smith

Research output: Contribution to journalArticle

163 Citations (Scopus)

Abstract

Using a monoclonal antibody to choline acetyltransferase, immunoreative synaptic boutons were identified in the neostriatum, cingulate cortex, basolateral nucleus of the amygdala, hippocampus and interpenduncular nucleus of the rat. The synapses were generally symmetrical although some asymmetrical membrane specializations were observed. Postsynaptic targets included perikarya, dendritic shafts and dendritic spines.

Original languageEnglish
Pages (from-to)69-76
Number of pages8
JournalBrain Research
Volume308
Issue number1
DOIs
Publication statusPublished - Aug 6 1984

Fingerprint

Neostriatum
Dendritic Spines
Choline O-Acetyltransferase
Gyrus Cinguli
Presynaptic Terminals
Amygdala
Synapses
Cholinergic Agents
Hippocampus
Monoclonal Antibodies
Electrons
Light
Membranes
Brain
Basolateral Nuclear Complex

Keywords

  • amygdala
  • choline acetyltransferase
  • cholinergic synapses
  • cingulate cortex
  • hippocampus
  • immunocytochemistry
  • interpeduncular nucleus
  • neostriatum

ASJC Scopus subject areas

  • Developmental Biology
  • Molecular Biology
  • Clinical Neurology
  • Neuroscience(all)

Cite this

Cholinergic synapses in the rat brain : a correlated light and electron microscopic immunohistochemical study employing a monoclonal antibody against choline acetyltransferase. / Wainer, B. H.; Bolam, J. P.; Freund, T.; Henderson, Z.; Totterdell, S.; Smith, A. D.

In: Brain Research, Vol. 308, No. 1, 06.08.1984, p. 69-76.

Research output: Contribution to journalArticle

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AU - Smith, A. D.

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