Cholecystokinin cholecystography: use of synthetic cholecystokinin octapeptide by different routes of administration

J. Lonovics, G. Narai, V. Varro

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Abstract

Theh Hungarian synthetic cholecystokinin octapeptide (CCK-OP) is a preparation with activity similar to that of the Squibb octapeptide. Its solution in physiological saline can be well sterilized and has satisfactory stability. Intravenous administration of this preparation to humans causes some unpleasant side-effects, which have not been observed in cases of subcutaneous, nasal or rectal administration. The cholecystokinetic activity is exerted rapidly and is long-lasting. Although subcutaneous administration is cheaper, for routine examinations the more convenient nasal route of administration seems to offer better perspectives. The CCK-OP is excellently applicable for contraction of the gallbladder, for visualization of the common bile duct in connection with per os cholecystography, and for assessment of the interrelation between gallbladder and gastroduodenum during simultaneous X-ray examination of the stomach.

Original languageEnglish
Pages (from-to)229-235
Number of pages7
JournalMateria Medica Polona
Volume12
Issue number4
Publication statusPublished - Dec 1 1980

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ASJC Scopus subject areas

  • Medicine(all)

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