Cholagogue-induced gallbladder emptying in the diagnosis of canine biliary obstruction

Ágnes Sterczer, Jeno Reiczigel, Roland Psáder, Kinga Pápa, Károly Vörös, Ákos Pap

Research output: Contribution to journalArticle

1 Citation (Scopus)


The efficacy of ultrasound-guided cholagogue-induced gallbladder emptying for differentiating obstructive from non-obstructive hepatobiliary diseases was studied in icteric dogs. In 7 healthy Beagle dogs, Lipofundin 20% infusion (2 ml/kg orally) evoked a vigorous gallbladder contraction of 44.2% (range: 35.3-57.6%) and proved to be a useful, well-tolerable meal for routine use. In 24 icteric dogs, gallbladder contraction was evoked by different cholagogues: the maximum reduction in gallbladder volume (%) for the three non-obstructive icteric dogs was 43.9% (range, 39.0-46.5%). The average gallbladder contraction of the 21 dogs with biliary obstruction was less than 5%. In conclusion, the stimulation of gallbladder contraction with orally applied magnesium sulphate (MgSO4) or Lipofundin can be well demonstrated by ultrasound in dogs. The examination of cholagogue-induced gallbladder emptying is a valuable technique in icteric patients to indicate surgical intervention.

Original languageEnglish
Pages (from-to)199-209
Number of pages11
JournalActa veterinaria Hungarica
Issue number2
Publication statusPublished - Jun 1 2012



  • Gallbladder volume
  • cholagogue
  • dog
  • icterus
  • ultrasound

ASJC Scopus subject areas

  • veterinary(all)

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