Cholagogue-induced gallbladder emptying in the diagnosis of canine biliary obstruction

Ágnes Sterczer, J. Reiczigel, Roland Psáder, Kinga Pápa, K. Vörös, A. Pap

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The efficacy of ultrasound-guided cholagogue-induced gallbladder emptying for differentiating obstructive from non-obstructive hepatobiliary diseases was studied in icteric dogs. In 7 healthy Beagle dogs, Lipofundin 20% infusion (2 ml/kg orally) evoked a vigorous gallbladder contraction of 44.2% (range: 35.3-57.6%) and proved to be a useful, well-tolerable meal for routine use. In 24 icteric dogs, gallbladder contraction was evoked by different cholagogues: the maximum reduction in gallbladder volume (%) for the three non-obstructive icteric dogs was 43.9% (range, 39.0-46.5%). The average gallbladder contraction of the 21 dogs with biliary obstruction was less than 5%. In conclusion, the stimulation of gallbladder contraction with orally applied magnesium sulphate (MgSO4) or Lipofundin can be well demonstrated by ultrasound in dogs. The examination of cholagogue-induced gallbladder emptying is a valuable technique in icteric patients to indicate surgical intervention.

Original languageEnglish
Pages (from-to)199-209
Number of pages11
JournalActa Veterinaria Hungarica
Volume60
Issue number2
DOIs
Publication statusPublished - Jun 1 2012

Fingerprint

Gallbladder Emptying
cholestasis
gall bladder
Canidae
Gallbladder
Dogs
dogs
Cholagogues and Choleretics
Magnesium Sulfate
magnesium sulfate
Meals
Beagle

Keywords

  • cholagogue
  • dog
  • Gallbladder volume
  • icterus
  • ultrasound

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Cholagogue-induced gallbladder emptying in the diagnosis of canine biliary obstruction. / Sterczer, Ágnes; Reiczigel, J.; Psáder, Roland; Pápa, Kinga; Vörös, K.; Pap, A.

In: Acta Veterinaria Hungarica, Vol. 60, No. 2, 01.06.2012, p. 199-209.

Research output: Contribution to journalArticle

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