Chlamydia pneumoniae in coronary bypass grafts of redo patients. The concepts of the 'adventitial baseline infection'

Tibor Glasz, Eszter Hortoványi, Géza Mózes, András Kiss, G. Lotz, Pál Kaposi Nagy, Ágnes Szik, Magdolna Kardos, I. Sziller, B. Nagy, Z. Bán, A. Tóth, Imre Kassai, F. Horkay, Gábor Dudás, A. Kádár

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The pathogenic role of Chlamydia pneumoniae in late coronary bypass graft failure has not yet been extensively investigated. We examined failed and new arterial/venous bypass grafts using immunohistochemistry, polymerase chain reaction (PCR), and serology. Thirty-four long-term failed grafts and 28 new grafts were examined in 21 patients undergoing redo coronary artery bypass grafting (CABG). Immunohistochemically, 28 (82%) failed grafts were positive in the intimal-medial compartment, and 33 grafts (97%) were positive for C. pneumoniae in the adventitia. Thirteen (46%) and 27 (96%) new grafts showed infection in the intima-media and in the adventitia, respectively (p

Original languageEnglish
Pages (from-to)609-618
Number of pages10
JournalPathology Research and Practice
Volume200
Issue number9
DOIs
Publication statusPublished - Sep 24 2004

Fingerprint

Chlamydophila pneumoniae
Adventitia
Transplants
Infection
Tunica Intima
Serology
Coronary Artery Bypass
Immunohistochemistry
Polymerase Chain Reaction

Keywords

  • Arteriosclerosis
  • Bypass
  • Chlamydia pneumoniae
  • Coronary disease
  • Late graft failure

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Chlamydia pneumoniae in coronary bypass grafts of redo patients. The concepts of the 'adventitial baseline infection'. / Glasz, Tibor; Hortoványi, Eszter; Mózes, Géza; Kiss, András; Lotz, G.; Kaposi Nagy, Pál; Szik, Ágnes; Kardos, Magdolna; Sziller, I.; Nagy, B.; Bán, Z.; Tóth, A.; Kassai, Imre; Horkay, F.; Dudás, Gábor; Kádár, A.

In: Pathology Research and Practice, Vol. 200, No. 9, 24.09.2004, p. 609-618.

Research output: Contribution to journalArticle

Glasz, Tibor ; Hortoványi, Eszter ; Mózes, Géza ; Kiss, András ; Lotz, G. ; Kaposi Nagy, Pál ; Szik, Ágnes ; Kardos, Magdolna ; Sziller, I. ; Nagy, B. ; Bán, Z. ; Tóth, A. ; Kassai, Imre ; Horkay, F. ; Dudás, Gábor ; Kádár, A. / Chlamydia pneumoniae in coronary bypass grafts of redo patients. The concepts of the 'adventitial baseline infection'. In: Pathology Research and Practice. 2004 ; Vol. 200, No. 9. pp. 609-618.
@article{dd67fb6b92724bb1a0c5679180259000,
title = "Chlamydia pneumoniae in coronary bypass grafts of redo patients. The concepts of the 'adventitial baseline infection'",
abstract = "The pathogenic role of Chlamydia pneumoniae in late coronary bypass graft failure has not yet been extensively investigated. We examined failed and new arterial/venous bypass grafts using immunohistochemistry, polymerase chain reaction (PCR), and serology. Thirty-four long-term failed grafts and 28 new grafts were examined in 21 patients undergoing redo coronary artery bypass grafting (CABG). Immunohistochemically, 28 (82{\%}) failed grafts were positive in the intimal-medial compartment, and 33 grafts (97{\%}) were positive for C. pneumoniae in the adventitia. Thirteen (46{\%}) and 27 (96{\%}) new grafts showed infection in the intima-media and in the adventitia, respectively (p",
keywords = "Arteriosclerosis, Bypass, Chlamydia pneumoniae, Coronary disease, Late graft failure",
author = "Tibor Glasz and Eszter Hortov{\'a}nyi and G{\'e}za M{\'o}zes and Andr{\'a}s Kiss and G. Lotz and {Kaposi Nagy}, P{\'a}l and {\'A}gnes Szik and Magdolna Kardos and I. Sziller and B. Nagy and Z. B{\'a}n and A. T{\'o}th and Imre Kassai and F. Horkay and G{\'a}bor Dud{\'a}s and A. K{\'a}d{\'a}r",
year = "2004",
month = "9",
day = "24",
doi = "10.1016/j.prp.2003.08.001",
language = "English",
volume = "200",
pages = "609--618",
journal = "Pathology Research and Practice",
issn = "0344-0338",
publisher = "Urban und Fischer Verlag GmbH und Co. KG",
number = "9",

}

TY - JOUR

T1 - Chlamydia pneumoniae in coronary bypass grafts of redo patients. The concepts of the 'adventitial baseline infection'

AU - Glasz, Tibor

AU - Hortoványi, Eszter

AU - Mózes, Géza

AU - Kiss, András

AU - Lotz, G.

AU - Kaposi Nagy, Pál

AU - Szik, Ágnes

AU - Kardos, Magdolna

AU - Sziller, I.

AU - Nagy, B.

AU - Bán, Z.

AU - Tóth, A.

AU - Kassai, Imre

AU - Horkay, F.

AU - Dudás, Gábor

AU - Kádár, A.

PY - 2004/9/24

Y1 - 2004/9/24

N2 - The pathogenic role of Chlamydia pneumoniae in late coronary bypass graft failure has not yet been extensively investigated. We examined failed and new arterial/venous bypass grafts using immunohistochemistry, polymerase chain reaction (PCR), and serology. Thirty-four long-term failed grafts and 28 new grafts were examined in 21 patients undergoing redo coronary artery bypass grafting (CABG). Immunohistochemically, 28 (82%) failed grafts were positive in the intimal-medial compartment, and 33 grafts (97%) were positive for C. pneumoniae in the adventitia. Thirteen (46%) and 27 (96%) new grafts showed infection in the intima-media and in the adventitia, respectively (p

AB - The pathogenic role of Chlamydia pneumoniae in late coronary bypass graft failure has not yet been extensively investigated. We examined failed and new arterial/venous bypass grafts using immunohistochemistry, polymerase chain reaction (PCR), and serology. Thirty-four long-term failed grafts and 28 new grafts were examined in 21 patients undergoing redo coronary artery bypass grafting (CABG). Immunohistochemically, 28 (82%) failed grafts were positive in the intimal-medial compartment, and 33 grafts (97%) were positive for C. pneumoniae in the adventitia. Thirteen (46%) and 27 (96%) new grafts showed infection in the intima-media and in the adventitia, respectively (p

KW - Arteriosclerosis

KW - Bypass

KW - Chlamydia pneumoniae

KW - Coronary disease

KW - Late graft failure

UR - http://www.scopus.com/inward/record.url?scp=4444356178&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=4444356178&partnerID=8YFLogxK

U2 - 10.1016/j.prp.2003.08.001

DO - 10.1016/j.prp.2003.08.001

M3 - Article

C2 - 15497773

AN - SCOPUS:4444356178

VL - 200

SP - 609

EP - 618

JO - Pathology Research and Practice

JF - Pathology Research and Practice

SN - 0344-0338

IS - 9

ER -