Chiral P-heterocycles: Efficient method for the resolution of 3-methyl-3-phospholene 1-oxides

Tibor Novak, J. Schindler, Viktória Ujj, M. Czugler, E. Fogassy, G. Keglevich

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The enantiomers of 1-aryl-, 1-alkyl- and 1-alkoxy-3-methyl-3-phospholene 1-oxides were separated in good yields and in high enantiomeric excesses (up to >99% ee) by resolution via formation of diastereomeric complexes with (-)-(4R,5R)-4,5-bis(diphenylhydroxymethyl)-2,2-dimethyldioxolane (TADDOL) or (-)-(2R,3R)-α,α,α′,α′-tetraphenyl-1, 4-dioxaspiro[4.5]decan-2,3-dimethanol.

Original languageEnglish
Pages (from-to)543-546
Number of pages4
JournalPhosphorus, Sulfur and Silicon and Related Elements
Volume183
Issue number2-3
DOIs
Publication statusPublished - Feb 2008

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Enantiomers
Oxides
alkoxyl radical

Keywords

  • Chiral P-heterocycles
  • Diastereomeric complex formation
  • Resolution
  • TADDOL

ASJC Scopus subject areas

  • Inorganic Chemistry

Cite this

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AU - Schindler, J.

AU - Ujj, Viktória

AU - Czugler, M.

AU - Fogassy, E.

AU - Keglevich, G.

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