Chinese herbs (Astragalus radix and Ganoderma lucidum) enhance immune response of carp, Cyprinus carpio, and protection against Aeromonas hydrophila

Guojun Yin, L. Ardó, K. D. Thompson, A. Adams, Z. Jeney, G. Jeney

Research output: Contribution to journalArticle

178 Citations (Scopus)

Abstract

The effect of Chinese herbs (Astragalus radix and Ganoderma lucidum) on immune response of carp was investigated. Fish were fed diets containing Astragalus (0.5%), Ganoderma (0.5%) and combination of two herbs (Astragalus 0.5% and Ganoderma 0.5%) for 5 weeks. Other groups of fish were vaccinated (i.p.) against Aeromonas hydrophila/Aeromonas salmonicida (Shering Plough, Essex, U.K.) at the beginning of the experiment and fed the same diets as described above. Control fish (negative control) and fish vaccinated only (positive control) were fed basal diets without supplements of herbs. The respiratory burst activity, phagocytosis, lysozyme activity and circulatory antibody titres in plasma were monitored. Following 5 weeks after feeding, fish were infected with A. hydrophila and mortalities were recorded. The results of this study showed that feeding non-vaccinated and vaccinated carp with combination of Astragalus and Ganoderma stimulated respiratory burst activity, phagocytosis of phagocytic cells in blood and lysozyme and circulatory antibody titres in plasma in vaccinated carp. Fish challenged with A. hydrophila had variable survival. The best survival (60%) was in vaccinated group fed with both herbs, while almost 90% of control fish (negative control) and 60% of fish vaccinated only (positive control) died.

Original languageEnglish
Pages (from-to)140-145
Number of pages6
JournalFish and Shellfish Immunology
Volume26
Issue number1
DOIs
Publication statusPublished - Jan 2009

Keywords

  • Aeromonas hydrophila
  • Astragalus radix
  • Common carp
  • Cyprinus carpio
  • Ganoderma lucidum
  • Immune response
  • Immunostimulant
  • Vaccine

ASJC Scopus subject areas

  • Environmental Chemistry
  • Aquatic Science

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