Chemotherapy of human non-Hodgkin lymphoma (NHL) xenografts

L. Kópper, P. Nagy, E. Magyarosy, J. Major

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Three human NHL (B-cell type) were established successfully as serially transplantable xenografts in artificially immunesuppressed CBA mice. All of them preserved the phenotypic characteristics of the original tumour even after several passages. The transplanted tumours were highly sensitive to cyclophosphamide and methotrexate, reflecting the results obtained in clinical practice, and relatively sensitive to dianhydrogalactitol.

Original languageEnglish
Pages (from-to)289-297
Number of pages9
JournalActa Morphologica Hungarica
Volume34
Issue number4
Publication statusPublished - 1986

Fingerprint

Heterografts
Non-Hodgkin's Lymphoma
Dianhydrogalactitol
Drug Therapy
Inbred CBA Mouse
Methotrexate
Cyclophosphamide
Neoplasms
B-Lymphocytes

ASJC Scopus subject areas

  • Anatomy

Cite this

Chemotherapy of human non-Hodgkin lymphoma (NHL) xenografts. / Kópper, L.; Nagy, P.; Magyarosy, E.; Major, J.

In: Acta Morphologica Hungarica, Vol. 34, No. 4, 1986, p. 289-297.

Research output: Contribution to journalArticle

@article{744bbc18307742ab852f5bb90694d82d,
title = "Chemotherapy of human non-Hodgkin lymphoma (NHL) xenografts",
abstract = "Three human NHL (B-cell type) were established successfully as serially transplantable xenografts in artificially immunesuppressed CBA mice. All of them preserved the phenotypic characteristics of the original tumour even after several passages. The transplanted tumours were highly sensitive to cyclophosphamide and methotrexate, reflecting the results obtained in clinical practice, and relatively sensitive to dianhydrogalactitol.",
author = "L. K{\'o}pper and P. Nagy and E. Magyarosy and J. Major",
year = "1986",
language = "English",
volume = "34",
pages = "289--297",
journal = "Acta Morphologica Hungarica",
issn = "0236-5391",
publisher = "Akademiai Kiado",
number = "4",

}

TY - JOUR

T1 - Chemotherapy of human non-Hodgkin lymphoma (NHL) xenografts

AU - Kópper, L.

AU - Nagy, P.

AU - Magyarosy, E.

AU - Major, J.

PY - 1986

Y1 - 1986

N2 - Three human NHL (B-cell type) were established successfully as serially transplantable xenografts in artificially immunesuppressed CBA mice. All of them preserved the phenotypic characteristics of the original tumour even after several passages. The transplanted tumours were highly sensitive to cyclophosphamide and methotrexate, reflecting the results obtained in clinical practice, and relatively sensitive to dianhydrogalactitol.

AB - Three human NHL (B-cell type) were established successfully as serially transplantable xenografts in artificially immunesuppressed CBA mice. All of them preserved the phenotypic characteristics of the original tumour even after several passages. The transplanted tumours were highly sensitive to cyclophosphamide and methotrexate, reflecting the results obtained in clinical practice, and relatively sensitive to dianhydrogalactitol.

UR - http://www.scopus.com/inward/record.url?scp=0023019291&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023019291&partnerID=8YFLogxK

M3 - Article

VL - 34

SP - 289

EP - 297

JO - Acta Morphologica Hungarica

JF - Acta Morphologica Hungarica

SN - 0236-5391

IS - 4

ER -