The chemotactic responses of polymorphonuclear leukocytes of normal subjects to corneal extracts of 0.2 and 0.4 mg/dl protein concentration were studied in blind-well type chemotactic chambers. E. coli endotoxin served as the positive, Rindex-5 fluid as the negative controls. The chemotactic response to corneal tissue extracts, as compared to random migration in the Rindex-5 medium, proved significant. It is suggested that chemotactic factors may be released from corneal grafts in vivo too, in consequence of diverse noxae. These factors are supposed to elicit a granulocytic invasion and to lead to an opacification of the graft as a result of a cellular reaction.
|Number of pages||5|
|Journal||Acta medica Academiae Scientiarum Hungaricae|
|Publication status||Published - Dec 1 1980|
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