Chemo-diversity and antiradical potential of twelve matricaria chamomilla L. Populations from Iran

Proof of ecological effects

Elahe Piri, Mohammad Mahmoodi Sourestani, Esmaeil Khaleghi, Javad Mottaghipisheh, Zoltán Péter Zomborszki, J. Hohmann, Dezső Csupor

Research output: Contribution to journalArticle

Abstract

Matricaria chamomilla L. is a popular medicinal herb that is used for healing various diseases and is widely distributed worldwide in temperate climate zones, and even in the subtropical climate of Southern and Western Iran. This study was aimed at comparing the volatile oil constituents, along with antiradical potential and HPLC analysis of methanolic extracts from twelve plant samples growing in Iran. The present research was carried out for the first time on these populations. Among seventeen identified volatile chemicals evaluated by GC/MS and GC/FID, representing 92.73–97.71% of the total oils, α-bisabolone oxide A (45.64–65.41%) was the major constituent, except in case of “Sarableh” as a new chemotype, where (E)- and (Z)-γ-bisabolene (42.76 and 40.08%, respectively) were the predominant components. Oxygenated sesquiterpenes (53.31–74.52%) were the most abundant compounds in the samples excluding “Sarableh” with 91.3% sesquiterpene hydrocarbons. “Sarableh” also exerted the most potent antioxidant capacity with EC50 = 7.76 ± 0.3 µg/mL and 6.51 ± 0.63 mmol TE (Trolox ® equivalents)/g. In addition, populations “Lali” and “Bagh Malek” contained the highest amounts of apigenin and luteolin with 1.19 ± 0.01 mg/g and 2.20 ± 0.0 mg/g of plant material, respectively. Our findings depict a clear correlation between phytochemical profiles and antiradical potential of M. chamomilla and geographical factors.

Original languageEnglish
Article number1315
JournalMolecules
Volume24
Issue number7
DOIs
Publication statusPublished - Apr 3 2019

Fingerprint

Matricaria
Iran
Sesquiterpenes
Climate
climate
oils
Apigenin
Luteolin
Plant Extracts
healing
antioxidants
Phytochemicals
Volatile Oils
Medicinal Plants
Hydrocarbons
Oxides
Population
Oils
Antioxidants
hydrocarbons

Keywords

  • Antiradical capacity
  • Ecological effects
  • Iranian populations
  • Matricaria chamomilla L
  • Volatile compounds

ASJC Scopus subject areas

  • Analytical Chemistry
  • Chemistry (miscellaneous)
  • Molecular Medicine
  • Pharmaceutical Science
  • Drug Discovery
  • Physical and Theoretical Chemistry
  • Organic Chemistry

Cite this

Chemo-diversity and antiradical potential of twelve matricaria chamomilla L. Populations from Iran : Proof of ecological effects. / Piri, Elahe; Sourestani, Mohammad Mahmoodi; Khaleghi, Esmaeil; Mottaghipisheh, Javad; Zomborszki, Zoltán Péter; Hohmann, J.; Csupor, Dezső.

In: Molecules, Vol. 24, No. 7, 1315, 03.04.2019.

Research output: Contribution to journalArticle

Piri, Elahe ; Sourestani, Mohammad Mahmoodi ; Khaleghi, Esmaeil ; Mottaghipisheh, Javad ; Zomborszki, Zoltán Péter ; Hohmann, J. ; Csupor, Dezső. / Chemo-diversity and antiradical potential of twelve matricaria chamomilla L. Populations from Iran : Proof of ecological effects. In: Molecules. 2019 ; Vol. 24, No. 7.
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abstract = "Matricaria chamomilla L. is a popular medicinal herb that is used for healing various diseases and is widely distributed worldwide in temperate climate zones, and even in the subtropical climate of Southern and Western Iran. This study was aimed at comparing the volatile oil constituents, along with antiradical potential and HPLC analysis of methanolic extracts from twelve plant samples growing in Iran. The present research was carried out for the first time on these populations. Among seventeen identified volatile chemicals evaluated by GC/MS and GC/FID, representing 92.73–97.71{\%} of the total oils, α-bisabolone oxide A (45.64–65.41{\%}) was the major constituent, except in case of “Sarableh” as a new chemotype, where (E)- and (Z)-γ-bisabolene (42.76 and 40.08{\%}, respectively) were the predominant components. Oxygenated sesquiterpenes (53.31–74.52{\%}) were the most abundant compounds in the samples excluding “Sarableh” with 91.3{\%} sesquiterpene hydrocarbons. “Sarableh” also exerted the most potent antioxidant capacity with EC50 = 7.76 ± 0.3 µg/mL and 6.51 ± 0.63 mmol TE (Trolox {\circledR} equivalents)/g. In addition, populations “Lali” and “Bagh Malek” contained the highest amounts of apigenin and luteolin with 1.19 ± 0.01 mg/g and 2.20 ± 0.0 mg/g of plant material, respectively. Our findings depict a clear correlation between phytochemical profiles and antiradical potential of M. chamomilla and geographical factors.",
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AU - Khaleghi, Esmaeil

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