Chemistry of Pyrido[1,2-b][1,2]oxazines, Pyrido[1,2-b][1,2]thiazines, Pyrido[1,2-b]pyridazines, and Their Benzologs: Part I

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The chapter focuses on the chemistry of the pyrido[l,2-b][1,2]oxazines, followed by pyrido[l,2-b][1,2]thiazines, pyrido[l,2-b]pyridazines, and their benzologs. Their structure is described based on thermodynamic aspects, theoretical calculations, UV, IR, mass, 1H NMR and 13C NMR spectroscopy. Their syntheses and reactions of the compounds are also discussed. The chapter also discusses their application and some important compounds such as 2,3-dihydro-4H-pyrido[1,2-b][1,2]oxazine, which is used as an organic oxyradical in the photocleavage of DNA and similar oligomers having a sugar-phosphate backbone. Some are patented as effective antimicrobial agents against gram-positive and gram-negative bacterial infections.

Original languageEnglish
Pages (from-to)89-128
Number of pages40
JournalAdvances in Heterocyclic Chemistry
Volume69
Issue numberC
DOIs
Publication statusPublished - Jan 1 1997

Fingerprint

Pyridazines
Oxazines
Antimicrobial agents
Oligomers
Nuclear magnetic resonance spectroscopy
DNA
Gram-Negative Bacterial Infections
Nuclear magnetic resonance
Thermodynamics
Sugar Phosphates
Anti-Infective Agents
Magnetic Resonance Spectroscopy
pyrido-1,2-thiazine
oxazine 1

ASJC Scopus subject areas

  • Biochemistry
  • Polymers and Plastics
  • Organic Chemistry

Cite this

@article{3c7a94408b814d3a9f59d1a1fcd5fe6c,
title = "Chemistry of Pyrido[1,2-b][1,2]oxazines, Pyrido[1,2-b][1,2]thiazines, Pyrido[1,2-b]pyridazines, and Their Benzologs: Part I",
abstract = "The chapter focuses on the chemistry of the pyrido[l,2-b][1,2]oxazines, followed by pyrido[l,2-b][1,2]thiazines, pyrido[l,2-b]pyridazines, and their benzologs. Their structure is described based on thermodynamic aspects, theoretical calculations, UV, IR, mass, 1H NMR and 13C NMR spectroscopy. Their syntheses and reactions of the compounds are also discussed. The chapter also discusses their application and some important compounds such as 2,3-dihydro-4H-pyrido[1,2-b][1,2]oxazine, which is used as an organic oxyradical in the photocleavage of DNA and similar oligomers having a sugar-phosphate backbone. Some are patented as effective antimicrobial agents against gram-positive and gram-negative bacterial infections.",
author = "I. Hermecz",
year = "1997",
month = "1",
day = "1",
doi = "10.1016/S0065-2725(08)60081-1",
language = "English",
volume = "69",
pages = "89--128",
journal = "Advances in Heterocyclic Chemistry",
issn = "0065-2725",
publisher = "Elsevier Inc.",
number = "C",

}

TY - JOUR

T1 - Chemistry of Pyrido[1,2-b][1,2]oxazines, Pyrido[1,2-b][1,2]thiazines, Pyrido[1,2-b]pyridazines, and Their Benzologs

T2 - Part I

AU - Hermecz, I.

PY - 1997/1/1

Y1 - 1997/1/1

N2 - The chapter focuses on the chemistry of the pyrido[l,2-b][1,2]oxazines, followed by pyrido[l,2-b][1,2]thiazines, pyrido[l,2-b]pyridazines, and their benzologs. Their structure is described based on thermodynamic aspects, theoretical calculations, UV, IR, mass, 1H NMR and 13C NMR spectroscopy. Their syntheses and reactions of the compounds are also discussed. The chapter also discusses their application and some important compounds such as 2,3-dihydro-4H-pyrido[1,2-b][1,2]oxazine, which is used as an organic oxyradical in the photocleavage of DNA and similar oligomers having a sugar-phosphate backbone. Some are patented as effective antimicrobial agents against gram-positive and gram-negative bacterial infections.

AB - The chapter focuses on the chemistry of the pyrido[l,2-b][1,2]oxazines, followed by pyrido[l,2-b][1,2]thiazines, pyrido[l,2-b]pyridazines, and their benzologs. Their structure is described based on thermodynamic aspects, theoretical calculations, UV, IR, mass, 1H NMR and 13C NMR spectroscopy. Their syntheses and reactions of the compounds are also discussed. The chapter also discusses their application and some important compounds such as 2,3-dihydro-4H-pyrido[1,2-b][1,2]oxazine, which is used as an organic oxyradical in the photocleavage of DNA and similar oligomers having a sugar-phosphate backbone. Some are patented as effective antimicrobial agents against gram-positive and gram-negative bacterial infections.

UR - http://www.scopus.com/inward/record.url?scp=85023083064&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85023083064&partnerID=8YFLogxK

U2 - 10.1016/S0065-2725(08)60081-1

DO - 10.1016/S0065-2725(08)60081-1

M3 - Article

AN - SCOPUS:85023083064

VL - 69

SP - 89

EP - 128

JO - Advances in Heterocyclic Chemistry

JF - Advances in Heterocyclic Chemistry

SN - 0065-2725

IS - C

ER -