Chemistry of norbornane/ene and heteronorbornane/ene β-amino acids

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15 Citations (Scopus)

Abstract

The structures, biological properties, preparations and synthetic applications of norbomane/ene bicyclic and heteroatom-bridged β-amino acids are disgussed. These compounds are rare and unique β-alanine derivatives which can be used as bifunctional synthons for the preparation of heterocycles. Through peptidation, they form oligopeptide-like molecules with special helical structures.

Original languageEnglish
Pages (from-to)173-185
Number of pages13
JournalCurrent Organic Synthesis
Volume5
Issue number2
DOIs
Publication statusPublished - May 1 2008

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Keywords

  • (Hetero)bicyclic β-amino acids
  • Biological activity
  • Heterocycles
  • Peptide syntheses
  • Retro diels-alder reactions
  • Ugi reactions

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry

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