Chemistry of indoles carrying a basic function. Part IV synthesis of D- norergoline and ergoline ring by Stobbe reaction

István Moldvai, Eszter Temesvári-Major, Eszter Gács-Baitz, Orsolya Egyed, Ágnes Gömöry, László Nyulászi, Csaba Szántay

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Starting from Uhle's ketone (2), pentacyclic lactone derivatives with D- norergoline ring (13 and 14) have been prepared by an unusual intramolecular Stobbe reaction of a succinic diester derivative (3a). The preparation of ergoline ring (1) itself was also achieved through modification of the reaction conditions.

Original languageEnglish
Pages (from-to)2321-2333
Number of pages13
JournalHeterocycles
Volume51
Issue number10
DOIs
Publication statusPublished - Oct 1 1999

ASJC Scopus subject areas

  • Analytical Chemistry
  • Pharmacology
  • Organic Chemistry

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