Chemistry of indoles carrying a basic function. Part 8: A new approach to the ergoline skeleton

Mária Incze, István Moldvai, Eszter Temesvári-Major, Gábor Dörnyei, M. Kajtár-Peredy, Csaba Szántay

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Starting from N-pivaloyl-Uhle's ketone a new synthetic approach to the ergoline skeleton has been elaborated. Ring D of the tetracyclic skeleton was formed by an intramolecular Dieckmann-condensation of a diester, obtained in a Reformatsky reaction of a properly substituted derivative of N-pivaloyl Uhle's ketone followed by elimination of water.

Original languageEnglish
Pages (from-to)4281-4286
Number of pages6
JournalTetrahedron
Volume59
Issue number24
DOIs
Publication statusPublished - Jun 9 2003

Fingerprint

Ergolines
Indoles
Ketones
Skeleton
Condensation
Derivatives
Water

Keywords

  • Alkaloids
  • Cyclisation
  • Dieckmann condensation
  • Ergolines
  • Modified Reformatsky reaction

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Chemistry of indoles carrying a basic function. Part 8 : A new approach to the ergoline skeleton. / Incze, Mária; Moldvai, István; Temesvári-Major, Eszter; Dörnyei, Gábor; Kajtár-Peredy, M.; Szántay, Csaba.

In: Tetrahedron, Vol. 59, No. 24, 09.06.2003, p. 4281-4286.

Research output: Contribution to journalArticle

Incze, Mária ; Moldvai, István ; Temesvári-Major, Eszter ; Dörnyei, Gábor ; Kajtár-Peredy, M. ; Szántay, Csaba. / Chemistry of indoles carrying a basic function. Part 8 : A new approach to the ergoline skeleton. In: Tetrahedron. 2003 ; Vol. 59, No. 24. pp. 4281-4286.
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