Chemistry of an Unexplored Heterocyclic Ring System: Versatile Synthesis of 5-Aryl-2,3,4-benzothiadiazepine 2,2-dioxides

Jõzsef Fetter, Ferenc Bertha, Balázs Molnár, Balázs Volk, Gyula Simig

Research output: Contribution to journalArticle

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Abstract

The article gives insight into the synthetic approach of a practically new heterocyclic ring system, 2,3,4-benzothiadiazepines. Starting from the easily available phthalides, an efficient synthesis of 5-aryl-2,3,4-benzothiadiazepine 2,2-dioxides is described here. Owing to their close structural similarity to 2,3-benzodiazepines and 2,3-benzodiazepine-4-ones, two well-known bioactive compound families, the new derivatives can be of importance in medicinal chemistry.

Original languageEnglish
Pages (from-to)1136-1142
Number of pages7
JournalJournal of Heterocyclic Chemistry
Volume52
Issue number4
DOIs
Publication statusPublished - Jul 1 2015

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ASJC Scopus subject areas

  • Organic Chemistry

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