Chemical synthesis of peptide libraries

Ferenc Sebestyén, Gábor Dibó, Attila Kovács, Árpd́ Furkua

Research output: Contribution to journalArticle

74 Citations (Scopus)

Abstract

The efficiency of the "portioning-mixing" method is demonstrated by the synthesis of more than one million hexapeptides in 5 days. An example is described to illustrate the possibility of completion of partial peptide libraries. Our method is also shown to be suitable to carry out binary peptide synthesis. In addition, a new screening method is outlined based on specific interaction of peptides with living cells.

Original languageEnglish
Pages (from-to)413-418
Number of pages6
JournalBioorganic and Medicinal Chemistry Letters
Volume3
Issue number3
DOIs
Publication statusPublished - Mar 1993

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmaceutical Science
  • Drug Discovery
  • Clinical Biochemistry
  • Organic Chemistry

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