Chemical, physical and biological approaches to prevent ochratoxin induced toxicoses in humans and animals

J. Varga, Sándor Kocinfé, Zsanett Péteri, C. Vágvölgyi, Beáta Tóth

Research output: Contribution to journalArticle

47 Citations (Scopus)

Abstract

Ochratoxins are polyketide derived fungal secondary metabolites with nephrotoxic, immunosuppressive, teratogenic, and carcinogenic properties. Ochratoxin- producing fungi may contaminate agricultural products in the field (preharvest spoilage), during storage (postharvest spoilage), or during processing. Ochratoxin contamination of foods and feeds poses a serious health hazard to animals and humans. Several strategies have been investigated for lowering the ochratoxin content in agricultural products. These strategies can be classified into three main categories: prevention of ochratoxin contamination, decontamination or detoxification of foods contaminated with ochratoxins, and inhibition of the absorption of consumed ochratoxins in the gastrointestinal tract. This paper gives an overview of the strategies that are promising with regard to lowering the ochratoxin burden of animals and humans.

Original languageEnglish
Pages (from-to)1718-1750
Number of pages33
JournalToxins
Volume2
Issue number7
DOIs
Publication statusPublished - Jul 2010

Fingerprint

Ochratoxins
Animals
Spoilage
Agricultural products
Contamination
Food Contamination
Polyketides
Health hazards
Detoxification
Decontamination
Immunosuppressive Agents
Metabolites
Fungi
Gastrointestinal Tract
Food
Health

Keywords

  • Adsorption
  • Detoxification
  • Ochratoxin
  • Spoilage

ASJC Scopus subject areas

  • Toxicology
  • Health, Toxicology and Mutagenesis

Cite this

Chemical, physical and biological approaches to prevent ochratoxin induced toxicoses in humans and animals. / Varga, J.; Kocinfé, Sándor; Péteri, Zsanett; Vágvölgyi, C.; Tóth, Beáta.

In: Toxins, Vol. 2, No. 7, 07.2010, p. 1718-1750.

Research output: Contribution to journalArticle

Varga, J. ; Kocinfé, Sándor ; Péteri, Zsanett ; Vágvölgyi, C. ; Tóth, Beáta. / Chemical, physical and biological approaches to prevent ochratoxin induced toxicoses in humans and animals. In: Toxins. 2010 ; Vol. 2, No. 7. pp. 1718-1750.
@article{52334ef7285349bd981bca2d4e7b8821,
title = "Chemical, physical and biological approaches to prevent ochratoxin induced toxicoses in humans and animals",
abstract = "Ochratoxins are polyketide derived fungal secondary metabolites with nephrotoxic, immunosuppressive, teratogenic, and carcinogenic properties. Ochratoxin- producing fungi may contaminate agricultural products in the field (preharvest spoilage), during storage (postharvest spoilage), or during processing. Ochratoxin contamination of foods and feeds poses a serious health hazard to animals and humans. Several strategies have been investigated for lowering the ochratoxin content in agricultural products. These strategies can be classified into three main categories: prevention of ochratoxin contamination, decontamination or detoxification of foods contaminated with ochratoxins, and inhibition of the absorption of consumed ochratoxins in the gastrointestinal tract. This paper gives an overview of the strategies that are promising with regard to lowering the ochratoxin burden of animals and humans.",
keywords = "Adsorption, Detoxification, Ochratoxin, Spoilage",
author = "J. Varga and S{\'a}ndor Kocinf{\'e} and Zsanett P{\'e}teri and C. V{\'a}gv{\"o}lgyi and Be{\'a}ta T{\'o}th",
year = "2010",
month = "7",
doi = "10.3390/toxins2071718",
language = "English",
volume = "2",
pages = "1718--1750",
journal = "Toxins",
issn = "2072-6651",
publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",
number = "7",

}

TY - JOUR

T1 - Chemical, physical and biological approaches to prevent ochratoxin induced toxicoses in humans and animals

AU - Varga, J.

AU - Kocinfé, Sándor

AU - Péteri, Zsanett

AU - Vágvölgyi, C.

AU - Tóth, Beáta

PY - 2010/7

Y1 - 2010/7

N2 - Ochratoxins are polyketide derived fungal secondary metabolites with nephrotoxic, immunosuppressive, teratogenic, and carcinogenic properties. Ochratoxin- producing fungi may contaminate agricultural products in the field (preharvest spoilage), during storage (postharvest spoilage), or during processing. Ochratoxin contamination of foods and feeds poses a serious health hazard to animals and humans. Several strategies have been investigated for lowering the ochratoxin content in agricultural products. These strategies can be classified into three main categories: prevention of ochratoxin contamination, decontamination or detoxification of foods contaminated with ochratoxins, and inhibition of the absorption of consumed ochratoxins in the gastrointestinal tract. This paper gives an overview of the strategies that are promising with regard to lowering the ochratoxin burden of animals and humans.

AB - Ochratoxins are polyketide derived fungal secondary metabolites with nephrotoxic, immunosuppressive, teratogenic, and carcinogenic properties. Ochratoxin- producing fungi may contaminate agricultural products in the field (preharvest spoilage), during storage (postharvest spoilage), or during processing. Ochratoxin contamination of foods and feeds poses a serious health hazard to animals and humans. Several strategies have been investigated for lowering the ochratoxin content in agricultural products. These strategies can be classified into three main categories: prevention of ochratoxin contamination, decontamination or detoxification of foods contaminated with ochratoxins, and inhibition of the absorption of consumed ochratoxins in the gastrointestinal tract. This paper gives an overview of the strategies that are promising with regard to lowering the ochratoxin burden of animals and humans.

KW - Adsorption

KW - Detoxification

KW - Ochratoxin

KW - Spoilage

UR - http://www.scopus.com/inward/record.url?scp=79952082797&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79952082797&partnerID=8YFLogxK

U2 - 10.3390/toxins2071718

DO - 10.3390/toxins2071718

M3 - Article

VL - 2

SP - 1718

EP - 1750

JO - Toxins

JF - Toxins

SN - 2072-6651

IS - 7

ER -