Chelate structure of a dirhodium-amino acid complex identified by chiroptical and NMR spectroscopy

Zs. Majer, Gábor Szilvágyi, László Benedek, A. Csámpai, M. Hollósi, E. Vass

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Dinuclear rhodium complexes have attracted considerable attention as a result of their chemical and biological reactivity. We report herein the synthesis and structural elucidation by combined spectroscopic methods of a new rhodium complex containing N-methyl-D-phenylalaninate (NMfO-) as a chiral ligand. It has been demonstrated that the structure of the chiral complex formed in water is independent of the ligand/metal molar ratio, the type of solvent, and reaction time, as shown by HPLC and ESI-MS analyses. The steric structure of the isolated and identified [Rh2(OAc) 2(OfMN)2] complex was determined by chiroptical (VCD, ECD) and NMR spectroscopy supported by DFT calculations. By this combined analysis, our studies have shown that the complex formed has two chiral ligands chelated through the O and N atoms of their carboxylate and sec-amino groups, respectively, in the vicinity of the two bridging acetate ligands. The steric structure and binding mode of the isolated new chiral dirhodium complex [Rh 2(OAc)2(OfMN)2] have been determined by chiroptical (VCD, ECD) and NMR spectroscopy supported by DFT calculations.

Original languageEnglish
Pages (from-to)3020-3027
Number of pages8
JournalEuropean Journal of Inorganic Chemistry
Issue number17
DOIs
Publication statusPublished - Jun 2013

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Nuclear magnetic resonance spectroscopy
Ligands
Amino Acids
Rhodium
Discrete Fourier transforms
Acetates
Metals
Atoms
Water

Keywords

  • Amino acids
  • Chirality
  • Circular dichroism
  • Rhodium
  • Structure elucidation

ASJC Scopus subject areas

  • Inorganic Chemistry

Cite this

Chelate structure of a dirhodium-amino acid complex identified by chiroptical and NMR spectroscopy. / Majer, Zs.; Szilvágyi, Gábor; Benedek, László; Csámpai, A.; Hollósi, M.; Vass, E.

In: European Journal of Inorganic Chemistry, No. 17, 06.2013, p. 3020-3027.

Research output: Contribution to journalArticle

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AU - Szilvágyi, Gábor

AU - Benedek, László

AU - Csámpai, A.

AU - Hollósi, M.

AU - Vass, E.

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AB - Dinuclear rhodium complexes have attracted considerable attention as a result of their chemical and biological reactivity. We report herein the synthesis and structural elucidation by combined spectroscopic methods of a new rhodium complex containing N-methyl-D-phenylalaninate (NMfO-) as a chiral ligand. It has been demonstrated that the structure of the chiral complex formed in water is independent of the ligand/metal molar ratio, the type of solvent, and reaction time, as shown by HPLC and ESI-MS analyses. The steric structure of the isolated and identified [Rh2(OAc) 2(OfMN)2] complex was determined by chiroptical (VCD, ECD) and NMR spectroscopy supported by DFT calculations. By this combined analysis, our studies have shown that the complex formed has two chiral ligands chelated through the O and N atoms of their carboxylate and sec-amino groups, respectively, in the vicinity of the two bridging acetate ligands. The steric structure and binding mode of the isolated new chiral dirhodium complex [Rh 2(OAc)2(OfMN)2] have been determined by chiroptical (VCD, ECD) and NMR spectroscopy supported by DFT calculations.

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