Charge-transfer chromatographic study of the interaction of commercial pesticides with hydroxypropyl-β-cyclodextrin

Y. Darwish, T. Cserháti

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The interaction between 33 commercial pesticides with hydroxypropyl-β-cyciodextrin (HPBCD) was studied by charge-transfer reversed-phase thin-layer chromatography using aqueous sodium chloride solutions as eluents. Each pesticide interacted with HPBCD, their lipophilicity linearly decreased with increasing HPBCD concentration, the pesticide - HPBCD complex (probably inclusion complex) always being more hydrophilic than the uncomplexed pesticide. In many cases the retention of pesticide increased with increasing concentration of salt in the eluent. This effect can be tentatively explained by the suppression of the dissociation of the polar groups in the solute molecules resulting in increased apparent lipophilicity. No significant correlation was found between lipophilicity and complex stability or between salting-out effect and lipophilicity, that is other than hydrophobic forces are involved in the pesticide - HPBCD interaction.

Original languageEnglish
Pages (from-to)139-147
Number of pages9
JournalToxicological and Environmental Chemistry
Volume54
Issue number1-4
DOIs
Publication statusPublished - Jan 1 1996

Keywords

  • Charge transfer chromatography pesticides
  • Hydroxypropyl-β-cyclodextrin
  • RPTLC

ASJC Scopus subject areas

  • Environmental Chemistry
  • Pollution
  • Health, Toxicology and Mutagenesis

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