Characterization of two different toxins of Wickerhamomyces anomalus (pichia anomala) VKM Y-159

Z. Farkas, J. Márki-Zay, J. Kucsera, C. Vágvölgyi, W. I. Golubev, I. Pfeiffer

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Wickerhamomyces anomalus VKM Y-159 strain produces two types of toxin designated as WAKT a and WAKT b, encoded by chromosomal genes. The WAKT a toxin is heat-labile, pronase sensitive acting in pH range 3-4 affecting on several yeasts including pathogenic Candida species while the WAKT b toxin is protease- and thermo-resistant, acting in pH range 3-7 on two species, Candida alai and Candida norvegica. The rapid decrease of the number of viable cells after toxin treatment demonstrates that both toxins have cytocidic effect.

Original languageEnglish
Pages (from-to)277-287
Number of pages11
JournalActa Biologica Hungarica
Volume63
Issue number2
DOIs
Publication statusPublished - May 1 2012

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Pichia
Candida
toxin
Pronase
Yeast
Peptide Hydrolases
Cell Count
Hot Temperature
Genes
Yeasts
yeast
gene

Keywords

  • killer toxins
  • Wickerhamomyces anomalus

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Environmental Science(all)
  • Neurology

Cite this

Characterization of two different toxins of Wickerhamomyces anomalus (pichia anomala) VKM Y-159. / Farkas, Z.; Márki-Zay, J.; Kucsera, J.; Vágvölgyi, C.; Golubev, W. I.; Pfeiffer, I.

In: Acta Biologica Hungarica, Vol. 63, No. 2, 01.05.2012, p. 277-287.

Research output: Contribution to journalArticle

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